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Yale Scientists Breach Brain Barriers to Attack Tumors

The brain is a sort of fortress, equipped with barriers designed to keep out dangerous pathogens. But protection comes at a cost: These barriers interfere with the immune system when faced with dire threats such glioblastoma, a deadly brain tumor for which there are few effective treatments.

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  • Experimental drug that targets liver fat may help prevent diabetes

    An experimental drug has reversed the build-up of fat in the liver and lowered blood levels of fatty substances including cholesterol in non-human primates. The build-up of fat in the liver, known as non-alcoholic fatty liver disease, affects 1 in 3 people and can lead to type 2 diabetes as well as heart and kidney disease.

    Source: NewScientist
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  • You have two ages, chronological and biological. Here's why it matters

    Essentially, everyone has two ages: a chronological age, how old the calendar says you are, and a phenotypic or biological age, basically the age at which your body functions as it compares to average fitness or health levels. Levine and her team identified nine biomarkers taken in a simple blood test that seemed to be the most influential on lifespan. The biomarkers include blood sugar, kidney and liver measures, and immune and inflammatory measures. Levine plugs those numbers into the computer, and the algorithm does the rest. People with a biological age lower than their chronological age have a lower mortality risk, while those aging older from a biological standpoint have a higher mortality risk and are potentially more prone to developing the diseases associated with the higher age range.

    Source: CNN
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Yale Center for
Research on Aging (Y-Age)

Yale School of Medicine
Department of Pathology
PO Box 208023
New Haven, CT 06520