2000
Accumulation of Synaptosomal-Associated Protein of 25 kDa (SNAP-25) and Other Proteins Associated with the Secretory Pathway in GH4C1 Cells Upon Treatment with Estradiol, Insulin, and Epidermal Growth Factor*
Lee M, Zhu Y, Sun Z, Rhee H, Jeromin A, Roder J, Dannies P. Accumulation of Synaptosomal-Associated Protein of 25 kDa (SNAP-25) and Other Proteins Associated with the Secretory Pathway in GH4C1 Cells Upon Treatment with Estradiol, Insulin, and Epidermal Growth Factor*. Endocrinology 2000, 141: 3485-3492. DOI: 10.1210/en.141.9.3485.Peer-Reviewed Original ResearchSNAP-25Secretory pathwaySynaptosomal-associated proteinSynaptotagmin IIIEpidermal growth factorCyclophilin BTreatment of GH4C1 cellsSecretory granulesSecretory granule accumulationGH4C1 cellsGlucose-regulated protein 94Rat pituitary GH4C1 cellsHormone-treated cellsInduction of proteinsPituitary GH4C1 cellsSynaptotagmin IRNA accumulationPlasma membraneSynaptotagminMessenger RNA accumulationInduced accumulationCell surfaceGranule accumulationProteinGrowth factor
1998
Stabilization of the Receptor Protein Tyrosine Phosphatase-Like Protein ICA512 in GH4C1 Cells upon Treatment with Estradiol, Insulin, and Epidermal Growth Factor*
Lee M, Dirkx R, Solimena M, Dannies P. Stabilization of the Receptor Protein Tyrosine Phosphatase-Like Protein ICA512 in GH4C1 Cells upon Treatment with Estradiol, Insulin, and Epidermal Growth Factor*. Endocrinology 1998, 139: 2727-2733. DOI: 10.1210/en.139.6.2727.Peer-Reviewed Original ResearchSecretory granule membranesEpidermal growth factorGTP-binding protein Rab3Granule membranesSecretory granule accumulationSecretory granule compartmentAssociated with secretory granule membranesTyrosine phosphatase-like proteinPhosphatase-like proteinGH4C1 cellsProlactin storageGH4C1 rat pituitary tumor cellsIncreased transcriptionPulse-chase procedureMature formRat pituitary tumor cellsSecretory granulesGranule compartmentGranule accumulationTreated cellsGrowth factorUntreated cellsPituitary tumor cellsMessenger RNAICA512