Andreas Coppi
Associate Research Scientist (Cardiovascular Medicine)Cards
About
Research
Publications
2026
Artificial intelligence-based automated interpretation of images of electrocardiograms: development and multinational validation of ECG-GPT
Khunte A, Sangha V, Oikonomou E, Dhingra L, Aminorroaya A, Coppi A, Shankar S, Rockers E, Mortazavi B, Bhatt D, Krumholz H, Al-Kindi S, Nadkarni G, Vaid A, Khera R. Artificial intelligence-based automated interpretation of images of electrocardiograms: development and multinational validation of ECG-GPT. European Heart Journal - Digital Health 2026, 7: ztag031. PMID: 41853639, PMCID: PMC12993923, DOI: 10.1093/ehjdh/ztag031.Peer-Reviewed Original ResearchTARGET-AI: A Foundational Approach for the Targeted Deployment of Artificial Intelligence Electrocardiography in the Electronic Health Record
Oikonomou E, Batinica B, Dhingra L, Aminorroaya A, Coppi A, Khera R. TARGET-AI: A Foundational Approach for the Targeted Deployment of Artificial Intelligence Electrocardiography in the Electronic Health Record. NEJM AI 2026, 3 DOI: 10.1056/aioa2500588.Peer-Reviewed Original ResearchClinical Trial Patient Matching: A Real-Time, Common Data Model and Artificial Intelligence–Driven System for Semiautomated Patient Prescreening in Cancer Clinical Trials
Gong G, Liu J, Pandya S, Taborda C, Wiesendanger N, Price N, Byron W, Coppi A, Young P, Wiess C, Dunning H, Barganier C, Brodeur R, Fischbach N, LoRusso P, Pusztai L, Kim S, Rozenblit M, Cecchini M, Mongiu A, Mendez L, Kaftan E, Torre C, Krumholz H, Krop I, Schulz W, Lustberg M, Kunz P. Clinical Trial Patient Matching: A Real-Time, Common Data Model and Artificial Intelligence–Driven System for Semiautomated Patient Prescreening in Cancer Clinical Trials. JCO Clinical Cancer Informatics 2026, 10: e2500262. PMID: 41512229, DOI: 10.1200/cci-25-00262.Peer-Reviewed Original ResearchAssessment of the integrity of real-time electronic health record data used in clinical research
Liu J, Pandya S, Coppi A, Young H, Krumholz H, Schulz W, Gong G. Assessment of the integrity of real-time electronic health record data used in clinical research. PLOS ONE 2026, 21: e0340287. PMID: 41511976, PMCID: PMC12788664, DOI: 10.1371/journal.pone.0340287.Peer-Reviewed Original Research
2025
Artificial intelligence-enabled electrocardiography and echocardiography to track preclinical progression of transthyretin amyloid cardiomyopathy
Oikonomou E, Sangha V, Shankar S, Coppi A, Krumholz H, Nasir K, Miller E, Gallegos Kattan C, Al-Mallah M, Al-Kindi S, Khera R. Artificial intelligence-enabled electrocardiography and echocardiography to track preclinical progression of transthyretin amyloid cardiomyopathy. European Heart Journal 2025, 46: 3651-3662. PMID: 40679604, PMCID: PMC12488324, DOI: 10.1093/eurheartj/ehaf450.Peer-Reviewed Original ResearchDevelopment and multinational validation of an ensemble deep learning algorithm for detecting and predicting structural heart disease using noisy single-lead electrocardiograms
Aminorroaya A, Dhingra L, Pedroso A, Shankar S, Coppi A, Khunte A, Foppa M, Brant L, Barreto S, Ribeiro A, Krumholz H, Oikonomou E, Khera R. Development and multinational validation of an ensemble deep learning algorithm for detecting and predicting structural heart disease using noisy single-lead electrocardiograms. European Heart Journal - Digital Health 2025, 6: 554-566. PMID: 40703117, PMCID: PMC12282373, DOI: 10.1093/ehjdh/ztaf034.Peer-Reviewed Original ResearchNirmatrelvir–ritonavir versus placebo–ritonavir in individuals with long COVID in the USA (PAX LC): a double-blind, randomised, placebo-controlled, phase 2, decentralised trial
Sawano M, Bhattacharjee B, Caraballo C, Khera R, Li S, Herrin J, Christian D, Coppi A, Warner F, Holub J, Henriquez Y, Johnson M, Goddard T, Rocco E, Hummel A, Mouslmani M, Hooper W, Putrino D, Carr K, Charnas L, De Jesus M, Nepert D, Abreu P, Ziegler F, Spertus J, Iwasaki A, Krumholz H. Nirmatrelvir–ritonavir versus placebo–ritonavir in individuals with long COVID in the USA (PAX LC): a double-blind, randomised, placebo-controlled, phase 2, decentralised trial. The Lancet Infectious Diseases 2025, 25: 936-946. PMID: 40188838, DOI: 10.1016/s1473-3099(25)00073-8.Peer-Reviewed Original ResearchEnsemble Deep Learning Algorithm for Structural Heart Disease Screening Using Electrocardiographic Images PRESENT SHD
Dhingra L, Aminorroaya A, Sangha V, Pedroso A, Shankar S, Coppi A, Foppa M, Brant L, Barreto S, Ribeiro A, Krumholz H, Oikonomou E, Khera R. Ensemble Deep Learning Algorithm for Structural Heart Disease Screening Using Electrocardiographic Images PRESENT SHD. Journal Of The American College Of Cardiology 2025, 85: 1302-1313. PMID: 40139886, PMCID: PMC12199746, DOI: 10.1016/j.jacc.2025.01.030.Peer-Reviewed Original ResearchAssessment of health conditions from patient electronic health record portals vs self-reported questionnaires: an analysis of the INSPIRE study
Khera R, Sawano M, Warner F, Coppi A, Pedroso A, Spatz E, Yu H, Gottlieb M, Saydah S, Stephens K, Rising K, Elmore J, Hill M, Idris A, Montoy J, O’Laughlin K, Weinstein R, Venkatesh A, Weinstein R, Gottlieb M, Santangelo M, Koo K, Derden A, Gottlieb M, Gatling K, Ahmed Z, Gomez C, Guzman D, Hassaballa M, Jerger R, Kaadan A, Venkatesh A, Spatz E, Kinsman J, Malicki C, Lin Z, Li S, Yu H, Mannan I, Yang Z, Liu M, Venkatesh A, Spatz E, Ulrich A, Kinsman J, Malicki C, Dorney J, Pierce S, Puente X, Salah W, Nichol G, Stephens K, Anderson J, Schiffgens M, Morse D, Adams K, Stober T, Maat Z, O’Laughlin K, Gentile N, Geyer R, Willis M, Zhang Z, Chang G, Lyon V, Klabbers R, Ruiz L, Malone K, Park J, Rising K, Kean E, Chang A, Renzi N, Watts P, Kelly M, Schaeffer K, Grau D, Cheng D, Shutty C, Charlton A, Shughart L, Shughart H, Amadio G, Miao J, Hannikainen P, Elmore J, Wisk L, L’Hommedieu M, Chandler C, Eguchi M, Roldan K, Moreno R, Rodriguez R, Wang R, Montoy J, Kemball R, Chan V, Chavez C, Wong A, Arreguin M, Hill M, Site R, Kane A, Nikonowicz P, Sapp S, Idris A, McDonald S, Gallegos D, Martin K, Saydah S, Plumb I, Hall A, Briggs-Hagen M. Assessment of health conditions from patient electronic health record portals vs self-reported questionnaires: an analysis of the INSPIRE study. Journal Of The American Medical Informatics Association 2025, 32: 784-794. PMID: 40036551, PMCID: PMC12012333, DOI: 10.1093/jamia/ocaf027.Peer-Reviewed Original ResearchArtificial intelligence-guided detection of under-recognised cardiomyopathies on point-of-care cardiac ultrasonography: a multicentre study
Oikonomou E, Vaid A, Holste G, Coppi A, McNamara R, Baloescu C, Krumholz H, Wang Z, Apakama D, Nadkarni G, Khera R. Artificial intelligence-guided detection of under-recognised cardiomyopathies on point-of-care cardiac ultrasonography: a multicentre study. The Lancet Digital Health 2025, 7: e113-e123. PMID: 39890242, PMCID: PMC12084816, DOI: 10.1016/s2589-7500(24)00249-8.Peer-Reviewed Original Research