Zika virus productively infects primary human placenta-specific macrophages
Jurado KA, Simoni MK, Tang Z, Uraki R, Hwang J, Householder S, Wu M, Lindenbach BD, Abrahams VM, Guller S, Fikrig E. Zika virus productively infects primary human placenta-specific macrophages. JCI Insight 2016, 1: e88461. PMID: 27595140, PMCID: PMC5007065, DOI: 10.1172/jci.insight.88461.Peer-Reviewed Original ResearchZika virus infectionHofbauer cellsVirus infectionFetal brainZika virusTerm placental villous explantsHuman placental macrophagesPlacental villous explantsPregnancy complicationsPlacental macrophagesPlacental barrierVillous explantsInfectious virusVillous fibroblastsCongenital defectsInfectionStrong associationMigratory activityVirusMacrophagesBrainCell typesCellsComplicationsFlaviviruses