Rev-erb Agonist Inhibits Chikungunya and O’nyong’nyong Virus Replication
Hwang J, Jiang A, Fikrig E. Rev-erb Agonist Inhibits Chikungunya and O’nyong’nyong Virus Replication. Open Forum Infectious Diseases 2018, 5: ofy315. PMID: 30568983, PMCID: PMC6293476, DOI: 10.1093/ofid/ofy315.Peer-Reviewed Original ResearchChikungunya virusSubset of patientsRecent global epidemicJoint painStructural protein synthesisSevere inflammationInflammatory responseMultiple alphavirusesViral RNA accumulationGlobal epidemicSynthetic agonistsVirus replicationCultured murine macrophagesMurine macrophagesSR9009AlphavirusesRelated virusesVirusProtein synthesisPainInflammationPatientsAgonistsMacrophagesRNA accumulation