2023
Positron Emission Tomography Imaging of Vessel Wall Matrix Metalloproteinase Activity in Abdominal Aortic Aneurysm
Toczek J, Gona K, Liu Y, Ahmad A, Ghim M, Ojha D, Kukreja G, Salarian M, Luehmann H, Heo G, Guzman R, Chaar C, Tellides G, Hassab A, Ye Y, Shoghi K, Zayed M, Gropler R, Sadeghi M. Positron Emission Tomography Imaging of Vessel Wall Matrix Metalloproteinase Activity in Abdominal Aortic Aneurysm. Circulation Cardiovascular Imaging 2023, 16: e014615. PMID: 36649454, PMCID: PMC9858355, DOI: 10.1161/circimaging.122.014615.Peer-Reviewed Original ResearchConceptsAbdominal aortic aneurysmHuman aortic tissueMMP activityAortic tissueAortic aneurysmMMP inhibitorsMurine modelMatrix metalloproteinasesPositron emission tomography/Toxicology studiesAortic MMP activityPositron emission tomography radioligandAngiotensin II infusionEmission tomography/Murine abdominal aortic aneurysmsBroad-spectrum MMP inhibitorMatrix metalloproteinase activityPositron emission tomography (PET) tracerPositron emission tomography (PET) imagingEmission Tomography ImagingPositron emission tomographyEmission tomography tracerII infusionRisk stratificationTomography/
2015
Corrigendum to “Disruption of TGF-<beta> signaling in smooth muscle cell prevents elastase-induced abdominal aortic aneurysm” [Biochem. Biophys. Res. Commun. 454 (1) (7 November 2014) 137–143]
Gao F, Chambon P, Offermanns S, Tellides G, Kong W, Zhang X, Li W. Corrigendum to “Disruption of TGF-signaling in smooth muscle cell prevents elastase-induced abdominal aortic aneurysm” [Biochem. Biophys. Res. Commun. 454 (1) (7 November 2014) 137–143]. Biochemical And Biophysical Research Communications 2015, 460: 887. DOI: 10.1016/j.bbrc.2015.04.001. Peer-Reviewed Original ResearchElastase-induced abdominal aortic aneurysmAbdominal aortic aneurysmDisruption of TGFAortic aneurysmAneurysms
2014
A haemodynamic predictor of intraluminal thrombus formation in abdominal aortic aneurysms
Di Achille P, Tellides G, Figueroa C, Humphrey J. A haemodynamic predictor of intraluminal thrombus formation in abdominal aortic aneurysms. Proceedings Of The Royal Society A 2014, 470: 20140163. DOI: 10.1098/rspa.2014.0163.Peer-Reviewed Original ResearchAbdominal aortic aneurysmIntraluminal thrombusAortic aneurysmThrombus formationUseful clinical predictorIntraluminal thrombus formationOscillatory shear indexClinical predictorsBlood-borne particlesHaemodynamic predictorsAbdominal aortaCarotid arteryHealthy subjectsThin thrombusClinical utilityHaemodynamic featuresComplex haemodynamicsThrombusTreatment planningComplex biomechanicsPatientsAneurysmsEndothelial mechanobiologyReliable predictorLesions