2014
MicroRNA silencing for cancer therapy targeted to the tumour microenvironment
Cheng CJ, Bahal R, Babar IA, Pincus Z, Barrera F, Liu C, Svoronos A, Braddock DT, Glazer PM, Engelman DM, Saltzman WM, Slack FJ. MicroRNA silencing for cancer therapy targeted to the tumour microenvironment. Nature 2014, 518: 107-110. PMID: 25409146, PMCID: PMC4367962, DOI: 10.1038/nature13905.Peer-Reviewed Original Research
1987
Amplification and deregulation of MYC following Epstein-Barr virus infection of a human B-cell line.
Lacy J, Summers W, Watson M, Glazer P, Summers W. Amplification and deregulation of MYC following Epstein-Barr virus infection of a human B-cell line. Proceedings Of The National Academy Of Sciences Of The United States Of America 1987, 84: 5838-5842. PMID: 3039510, PMCID: PMC298958, DOI: 10.1073/pnas.84.16.5838.Peer-Reviewed Original ResearchConceptsBurkitt's lymphomaEBV infectionB cell linesEpstein-Barr virus infectionEBV-negative Burkitt lymphomasEBV-positive sublinesEpstein-Barr virusAmplification of MYCRole of EBVMYC expressionPositive Burkitt's lymphomaHuman B cell linesDeregulation of MYCVirus infectionVitro infectionInfectionEBVAltered expressionBJAB cellsMYC transcriptionVirusMYC oncogeneMYC locusMYCCells
1985
Oncogene Expression in Isogenic, EBV-Positive and -Negative Burkitt Lymphoma Cell Lines
Glazer P, Summers W. Oncogene Expression in Isogenic, EBV-Positive and -Negative Burkitt Lymphoma Cell Lines. Intervirology 1985, 23: 82-89. PMID: 2984143, DOI: 10.1159/000149589.Peer-Reviewed Original ResearchConceptsEpstein-Barr virusNegative Burkitt lymphoma cell lineCell linesBJAB cellsOncogene expressionC-MycBurkitt's lymphoma cell linesMechanism of actionEBV infectionBL cell linesEBV-positiveC-myc expressionLymphoma cell linesLymphoid cellsOncogene c-mycBL cellsElevated expressionNormal karyotypeInitial reportMode of actionChromosomal translocationsBJABChromosome 8Ha-rasCellular oncogenes