Adel Bassily-Marcus, MD
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About
Research
Publications
2025
Barriers to Mobility in the ICU: Insights from Severe COVID-19 and Implications for Improving Patient Outcomes
Kalbian I, Delgado A, Barchuk S, Cohen S, Bassily-Marcus A, Tabacof L, Spielman L, Dams-O’Connor K, Kohli-Seth R, Dangayach N, Shetreat-Klein A, Escalon M. Barriers to Mobility in the ICU: Insights from Severe COVID-19 and Implications for Improving Patient Outcomes. Archives Of Rehabilitation Research And Clinical Translation 2025, 7: 100537. DOI: 10.1016/j.arrct.2025.100537.Peer-Reviewed Original ResearchIntensive care unitMobility outcomesMobility statusIntensive care unit mobilityOutcome measures Primary outcome measuresIntensive care unit visitsPhysical therapy visitsPostintensive care syndromeHospital lengthRichmond Agitation Sedation ScaleBody mass indexRisk of ICU-acquired weaknessICU-acquired weaknessPrimary outcome measureLong-term disabilityAPACHE-III scoresTherapy visitsHospital length of stayLength of stayEligible visitsCoarsened exact matchingPatient levelOutcome measuresIntensive care unit patientsTertiary care centerSociety of Critical Care Medicine 2024 Guidelines on Adult ICU Design
Hamilton D, Gary J, Scruth E, Anderson H, Cadenhead C, Oczkowski S, Lau V, Adler J, Bassily-Marcus A, Bassin B, Boyd J, Busl K, Crabb J, Harvey C, Hecht J, Herweijer M, Gunnerson K, Ibrahim A, Jabaley C, Kaplan L, Monchar S, Moody A, Read J, Renne B, Sarosi M, Swoboda S, Thompson-Brazill K, Wells C, Anderson D. Society of Critical Care Medicine 2024 Guidelines on Adult ICU Design. Critical Care Medicine 2025, 53: e690-e700. PMID: 39982130, DOI: 10.1097/ccm.0000000000006572.Peer-Reviewed Original ResearchConceptsICU designPatient- and family-centered careHealthcare architectsGuideline panelPractice statementsFamily-centered careSociety of Critical Care MedicineQuality of evidenceEvidence-based recommendationsCritical care medicineRecommendations AssessmentDatabase inceptionSurge capacityClinical professionalsPatient roomsPanel consensusCare medicineInsufficient evidenceInterventionHealthcareFlexible surge capacityEnhance sleepPICO questionICUExpert guidanceSociety of Critical Care Medicine 2024 Guidelines on Adult ICU Design: Executive Summary
Hamilton D, Gary J, Scruth E, Anderson H, Cadenhead C, Oczkowski S, Lau V, Adler J, Bassily-Marcus A, Bassin B, Boyd J, Busl K, Crabb J, Harvey C, Hecht J, Herweijer M, Gunnerson K, Ibrahim A, Jabaley C, Kaplan L, Monchar S, Moody A, Read J, Renne B, Sarosi M, Swoboda S, Thompson-Brazill K, Wells C, Anderson D. Society of Critical Care Medicine 2024 Guidelines on Adult ICU Design: Executive Summary. Critical Care Medicine 2025, 53: e683-e689. PMID: 39982134, DOI: 10.1097/ccm.0000000000006571.Peer-Reviewed Original Research
2024
Ultrasound-guided Axillary Artery Catheter Placement and Associated Complications in Critically Ill Patients
Cardona S, Gross A, Yu A, Bassily-Marcus A, Oropello J, Manasia A. Ultrasound-guided Axillary Artery Catheter Placement and Associated Complications in Critically Ill Patients. Journal Of Intensive Care Medicine 2024, 39: 916-921. PMID: 38794858, DOI: 10.1177/08850666241257417.Peer-Reviewed Original ResearchConceptsArtery catheter placementCritically ill patientsCatheter placementBody mass indexCatheter malfunctionArtery catheterVascular complicationsIll patientsMedian body mass indexCenter of patientsCatheter related complicationsRate of complicationsTertiary care centerIntensive care unitFemoral artery accessMedian ageAssociated complicationsRelated complicationsRetrospective studySurgical interventionCompartment syndromeUnivariate analysisMultiple cathetersMass indexClinical variablesThe COVID-19 Tracheostomy Experience at a Large Academic Medical Center in New York during the First Year
Patel D, Devivo A, Leibner E, Shittu A, Govindarajulu U, Tandon P, Lee D, Owen R, Fernandez-Ranvier G, Hiensch R, Marin M, Kohli-Seth R, Bassily-Marcus A. The COVID-19 Tracheostomy Experience at a Large Academic Medical Center in New York during the First Year. Journal Of Clinical Medicine 2024, 13: 2130. PMID: 38610895, PMCID: PMC11012500, DOI: 10.3390/jcm13072130.Peer-Reviewed Original ResearchIntensive care unitMount Sinai HospitalCare unitEarly tracheostomyMechanical ventilationRetrospective analysis of outcomesDuration of mechanical ventilationPatients admitted to intensive careIntensive care unit length of stayUnit length of stayReduced intensive care unit length of stayReduced duration of mechanical ventilationIntensive care unit lengthSinai HospitalReduced intensive care unit lengthAdult intensive care unitAnalysis of outcomesNew YorkLength of stayNew York CityReduce hospital lengthVentilatory supportClinical outcomesLaboratory valuesRetrospective analysis
2023
First case of rapidly fatal mpox from secondary (household) transmission in a kidney transplant recipient
Fuller R, Cederroth T, Patel G, Reidy J, Patiño L, Ramírez J, Bassily-Marcus A, Paniz-Mondolfi A. First case of rapidly fatal mpox from secondary (household) transmission in a kidney transplant recipient. American Journal Of Transplantation 2023, 23: 1995-1999. PMID: 37516244, DOI: 10.1016/j.ajt.2023.07.017.Peer-Reviewed Original ResearchConceptsSolid organ transplant recipientsOrgan transplant recipientsKidney transplant recipientsTransplant recipientsMale kidney transplant recipientsCases of mpoxGenomic analysisLaboratory findingsFatal courseProphylaxis effortsPublic health authoritiesPatient populationHousehold contactsRisk factorsAutopsy findingsHealth authoritiesRecipientsPatientsMPOXDiseaseMenGenomeSecondary transmissionIntravenous aviptadil and remdesivir for treatment of COVID-19-associated hypoxaemic respiratory failure in the USA (TESICO): a randomised, placebo-controlled trial
Brown S, Barkauskas C, Grund B, Sharma S, Phillips A, Leither L, Peltan I, Lanspa M, Gilstrap D, Mourad A, Lane K, Beitler J, Serra A, Garcia I, Almasri E, Fayed M, Hubel K, Harris E, Middleton E, Barrios M, Mathews K, Goel N, Acquah S, Mosier J, Hypes C, Campbell E, Khan A, Hough C, Wilson J, Levitt J, Duggal A, Dugar S, Goodwin A, Terry C, Chen P, Torbati S, Iyer N, Sandkovsky U, Johnson N, Robinson B, Matthay M, Aggarwal N, Douglas I, Casey J, Hache-Marliere M, Youssef J, Nkemdirim W, Leshnower B, Awan O, Pannu S, O'Mahony D, Manian P, Hayanga J, Wortmann G, Tomazini B, Miller R, Jensen J, Murray D, Bickell N, Zatakia J, Burris S, Higgs E, Natarajan V, Dewar R, Schechner A, Kang N, Arenas-Pinto A, Hudson F, Ginde A, Self W, Rogers A, Oldmixon C, Morin H, Sanchez A, Weintrob A, Cavalcanti A, Davis-Karim A, Engen N, Denning E, Thompson B, Gelijns A, Kan V, Davey V, Lundgren J, Babiker A, Neaton J, Lane H, Group A, Tierney J, Vogel S, McNay L, Cahill K, Crew P, Sardana R, Raim S, Shaw-Saliba K, Atri N, Miller M, Vallee D, Chung L, Delph Y, Adam S, Read S, Draghia-Akli R, Harrigan R, Carlsen A, Carter A, DuChene A, Eckroth K, Frase A, Harrison M, Meger S, Quan K, Quan S, Reilly C, Thompson G, Walski J, Moskowitz A, Bagiella E, Moquete E, O'Sullivan K, Marks M, Accardi E, Kinzel E, Bedoya G, Gupta L, Overbey J, Padillia M, Santos M, Gillinov M, Miller M, Taddei-Peters W, Fenton K, Smith P, Vekstein A, Ko E, Al-Hegelan M, McGowan L, Motta M, Howell S, Bent F, Kalager R, Chan E, Aloor H, Griffin S, Covington A, McLendon-Arvik B, Bussadori B, Miller-Bell M, Sampey C, Gaver V, Hollister B, Giangiacomo D, Pauley A, Patel A, Classon C, Frazier M, Osborne R, Conlon D, Joshi M, Gottlieb R, Mack M, Berhe M, Haley C, Dishner E, Bettacchi C, Golden K, Duhaime E, Ryan M, Tallmadge C, Estrada L, Jones F, Villa S, Wang S, Robert R, Coleman T, Clariday L, Baker R, Hurutado-Rodriguez M, Iram N, Fresnedo M, Davis A, Leonard K, Ramierez N, Thammavong J, Duque K, Turner E, Fisher T, Robinson D, Ransom D, Maldonado N, Lusk E, Killian A, Palacios A, Solis E, Jerrow J, Watts M, Whitacre H, Cothran E, Bender W, Miller J, Nugent K, Farrington W, Baio K, McBride M, Fielding M, Mathewson S, Porte K, Haley E, Rogers S, Tyler D, Perin E, Costello B, Postalian A, Sohail R, Hinsu P, Watson C, Kappenman C, Chen J, Walker K, Fink M, Phillip G, Mahon K, Sturgis L, Maher P, Rogers L, Ng N, Marshall J, Bassily-Marcus A, Cohen I, Ramoo S, Malhotra A, Kessler J, Goetz R, Badhwar V, Hayanga J, Sutton L, Williams R, Bartolo E, Walker D, Bunner R, Glaze C, Aucremanne T, Bishop J, Kelley M, Peterson A, Sauerborn E, Reckart R, Miller B, Mittel A, Darmanian A, Rosen A, Madahar P, Schicchi J, Gosek K, Dzierba A, Wahab R, Eng C, Al-Saadi M, Zahiruddin F, Syed M, George M, Patel V, Onwunyi C, da Costa R, North C, Ringwood N, Fitzgerald L, Muzikansky A, Morse R, Brower R, Reineck L, Bienstock K, Hou P, Steingrub J, Tidswell M, Kozikowski L, Kardos C, De Souza L, Talmor D, Shapiro N, Hibbert K, Brait K, Kone M, Hendey G, Kangelaris K, Ashktorab K, Gropper R, Agrawal A, Timothy K, Zhou H, Hughes A, Garcia R, Torres A, Hernandez-Almaraz M, Vojnik R, Perez C, McDowell J, Chang S, Vargas J, Moss M, McKeehan J, Higgins C, Johnson E, Slaughter S, Wyles D, Hiller T, Oakes J, Garcia A, Gravitz S, Lyle C, Swanson D, Gong M, Richardson L, Chen J, Moskowitz A, Mohamed A, Lopez B, Amosu O, Tzehaie H, Boujid S, Bixby B, Lopez A, Durley J, Gilson B, Hite R, Wang H, Wiedemann H, Mehkri O, Ashok K, King A, Brennan C, Exline M, Englert J, Karow S, Schwartz E, So P, So M, Krol O, Parra G, Mills E, Oh M, Pena J, Martínez J, Jackman S, Bayoumi E, Pascual E, Caudill A, Chen P, Richardson T, Clapham G, Herrera L, Ojukwu C, Fine D, Gomez M, Choi-Kuaea Y, Weissberg G, Isip K, Mattison B, Tran D, Dukov J, Chung P, Kang B, Escobar L, Tran T, Baig S, Wallick J, Duven A, Fletcher D, Gundel S, Fuentes M, Newton M, Peterson E, Jiang K, Files D, Miller C, Lematty C, Rasberry A, Warden A, Bledsoe J, Knowlton K, Knox D, Klippel C, Armbruster B, Applegate D, Imel K, Fergus M, Rahmati K, Jensen H, Aston V, Jeppson J, Marshall J, Lumpkin J, Smith C, Burke T, Gray A, Paine R, Callahan S, Yamane M, Waddoups L, Rice T, Johnson J, Gray C, Hays M, Roth M, Musick S, Miller K, Semler M, Popielski L, Kambo A, Viens K, Turner M, Vjecha M, Denyer R, Khosla R, Rajendran B, Gonzales M, Moriarty T, Biswas K, Harrington C, Garcia A, Bremer T, Burke T, Koker B, Pittman D, Vasudeva S, Anholm J, Specht L, Rodriguez A, Ngo H, Duong L, Previte M, Raben D, Nielsen C, Larsen J, Peters L, Matthews G, Kelleher A, Polizzotto M, Carey C, Chang C, Dharan N, Hough S, Virachit S, Davidson S, Bice D, Ognenovska K, Cabrera G, Flynn R, Abdelghany M, Baseler B, Teitelbaum M, Holley H, Jankelevich S, Adams A, Becker N, Doleny S, Hissey D, Simpson S, Kim M, Beeler J, Harmon L, Vanderpuye S, Yeon L, Frye L, Rudzinski E, Buehn M, Eccard-Koons V, Frary S, MacDonalad L, Cash J, Hoopengardner L, Linton J, Nelson M, Spinelli-Nadzam M, Proffitt C, Lee C, Engel T, Fontaine L, Osborne C, Hohn M, Galcik M, Thompson D, Sandrus J, Manchard J, Giri J, Kopka S, Chang W, Sherman B, Rupert A, Highbarger H, Baseler M, Lallemand P, Rehman T, Imamichi T, Laverdure S, Paudel S, Cook K, Haupt K, Hazen A, Badralmaa Y, Highbarger J, McCormack A, Gerry N, Smith K, Patel B, Domeraski N, Hoover M, DuChateau N, Flosi A, Nelson R, Stojanovic J, Wenner C. Intravenous aviptadil and remdesivir for treatment of COVID-19-associated hypoxaemic respiratory failure in the USA (TESICO): a randomised, placebo-controlled trial. The Lancet Respiratory Medicine 2023, 11: 791-803. PMID: 37348524, PMCID: PMC10527239, DOI: 10.1016/s2213-2600(23)00147-9.Peer-Reviewed Original ResearchConceptsAcute hypoxaemic respiratory failureHypoxaemic respiratory failureMatching placeboRespiratory failurePlacebo groupAdverse eventsOff oxygenModified intention-to-treat populationOdds ratioAcute hypoxemic respiratory failureIntention-to-treat populationModified intention-to-treat analysisHigh-flow nasal oxygenInfusion days 1Daily maintenance doseHypoxemic respiratory failurePlacebo-controlled trialDisease severityPrimary efficacy endpointInvasive mechanical ventilationBaseline disease severityIntention-to-treat analysisIntensive care unitSARS-CoV-2 infectionHospitalised adult patients
2022
COVID-19 and the Electronic Health Record: Tool Design and Evolution at the U.S. Pandemic Epicenter
Tsega S, Vijayaraghavan M, Chronister M, Srinivas S, Bassily-Marcus A, Gumprecht J, Shetreat-Klein A, Darrow B, Craven C. COVID-19 and the Electronic Health Record: Tool Design and Evolution at the U.S. Pandemic Epicenter. ACI Open 2022, 06: e85-e93. DOI: 10.1055/s-0042-1756435.Peer-Reviewed Original ResearchElectronic health recordsCare pathwaysMount Sinai Health SystemEHR toolsSinai Health SystemHealth recordsHealth systemElectronic health record toolsInpatient electronic health recordsChief Medical Information OfficerIntegrated care pathwayComprehensive care pathwayRobust care pathwaysReal-time clinical dataClinician-facingEarly pandemic monthsCare standardsInpatient ordersInpatient settingCare pathPatient surgeClinical informaticistsClinical knowledgeNew York CityInformaticists
2021
Prognostic Value of Electrocardiographic QRS Diminution in Patients Hospitalized With COVID-19 or Influenza
Lampert J, Miller M, Halperin J, Oates C, Giustino G, Nelson K, Feinman J, Kocovic N, Pulaski M, Musikantow D, Turagam M, Sofi A, Choudry S, Langan M, Koruth J, Whang W, Miller M, Dukkipati S, Bassily-Marcus A, Kohli-Seth R, Goldman M, Reddy V. Prognostic Value of Electrocardiographic QRS Diminution in Patients Hospitalized With COVID-19 or Influenza. The American Journal Of Cardiology 2021, 159: 129-137. PMID: 34579830, PMCID: PMC8349698, DOI: 10.1016/j.amjcard.2021.07.048.Peer-Reviewed Original ResearchConceptsCourse of COVID-19 infectionQRS amplitudeBaseline clinical variablesFollow-up electrocardiogramsPredictors of deathC-reactive proteinAssociated with mortalityInfluenza infectionVasopressor requirementsPeak troponinConsecutive adultsPrognostic valueMedian timeClinical decompensationD-dimerPrognostic utilityClinical reassessmentCOVID-19 infectionPrognostic toolClinical variablesInfluenzaPrecordial leadsPatientsSurface electrocardiogramQRS complex amplitudeProlonged Anaphylaxis to Pfizer Coronavirus Disease 2019 Vaccine: A Case Report and Mechanism of Action
Frank A, Radparvar S, Manasia A, Bassily-Marcus A, Kohli-Seth R. Prolonged Anaphylaxis to Pfizer Coronavirus Disease 2019 Vaccine: A Case Report and Mechanism of Action. Critical Care Explorations 2021, 3: e0397. PMID: 33834172, PMCID: PMC8021358, DOI: 10.1097/cce.0000000000000397.Peer-Reviewed Original ResearchMessenger RNA-based vaccinesEtiology of anaphylaxisRate of anaphylaxisCritical care managementCenters for Disease Control and PreventionEmergency use authorizationProtracted anaphylaxisDisease Control and PreventionIV steroidsRNA-based vaccinesMechanism of actionSafety profilePatient's anaphylaxisCase reportControl and PreventionRespiratory distressAnaphylactic reactionsClinical trialsEpinephrine infusionCoronavirus diseaseUnique caseAnaphylaxisAllergic reactionsPatientsVaccine prototype
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