2024
Safety Profile Comparison of 2 Smooth Tissue Expander Types
Almeida M, Alper D, Williams M, Shah R, Ihnat J, Hu K, Parikh N, Alperovich M. Safety Profile Comparison of 2 Smooth Tissue Expander Types. Annals Of Plastic Surgery 2024, 93: 178-182. PMID: 38980932, DOI: 10.1097/sap.0000000000004019.Peer-Reviewed Original ResearchConceptsBody mass indexComplication rateDrain durationMass indexAcellular dermal matrix useRetrospective review of patientsReview of patientsHigher body mass indexSmooth tissue expandersPain scoresChemotherapy exposureRetrospective reviewCapsular contractureSmooth implantsSafety profileWound breakdownFilling volumePatient comorbiditiesPerioperative informationCancer characteristicsMultivariate analysisComplicationsTissue expanderRadiation exposureMatrix use
2020
Neurologic Characterization of Craniosynostosis: Can Direct Brain Recordings Predict Language Development?
Wu R, Nie J, Abraham P, Halligan T, Gabrick K, Peck CJ, Sawh-Martinez R, Steinbacher DM, Alperovich M, McPartland J, Persing JA. Neurologic Characterization of Craniosynostosis: Can Direct Brain Recordings Predict Language Development? Journal Of Craniofacial Surgery 2020, 32: 78-82. PMID: 32941205, DOI: 10.1097/scs.0000000000007004.Peer-Reviewed Original ResearchConceptsNeural responsesLanguage deficitsLanguage developmentERP assessmentMetopic patientsMismatch negativity waveLarger negative amplitudesLong-term cognitionLanguage achievementCognitive outcomesMMNBrain recordingsInfant developmentBayley ScalesNegative amplitudeBSID scoresEEG testingBSIDDeficitsElectroencephalogramNeurocognitionCognitionSpeechStimuliYears of ageRisk of peri-operative complications in children receiving preoperative steroids
Mets EJ, Chouairi F, Mirza H, Allam O, Park KE, Junn A, Alperovich M. Risk of peri-operative complications in children receiving preoperative steroids. Pediatric Surgery International 2020, 36: 1345-1352. PMID: 32918623, DOI: 10.1007/s00383-020-04742-9.Peer-Reviewed Original ResearchConceptsAdverse eventsPediatric patientsSteroid usePreoperative steroidsNational Surgical Quality Improvement Project Pediatric databaseThirty-day adverse eventsPropensity scorePostoperative adverse eventsPeri-operative complicationsPediatric surgery patientsSimilar larger studiesMore comorbiditiesPerioperative impactHospital stayPerioperative complicationsAdult patientsPatient demographicsSteroid treatmentSurgery patientsSurgical variablesWound dehiscenceSurgical outcomesPediatric databasePatientsLarger studySpring-Assisted Strip Craniectomy Versus Cranial Vault Remodeling: Long-Term Psychological, Behavioral, and Executive Function Outcomes.
Chandler L, Allam O, Park KE, Smetona J, Gabrick KS, Wu RT, Morgan C, Park SE, Chapman LA, Couture DE, David LR, Runyan CM, Persing JA, Alperovich M. Spring-Assisted Strip Craniectomy Versus Cranial Vault Remodeling: Long-Term Psychological, Behavioral, and Executive Function Outcomes. Journal Of Craniofacial Surgery 2020, 31: 2101-2105. PMID: 32890160, DOI: 10.1097/scs.0000000000006806.Peer-Reviewed Original ResearchConceptsExecutive function outcomesExecutive functioning skillsBehavior Rating InventoryBehavior Assessment SystemSocial withdrawal symptomsExecutive functionRating InventoryBASC-2Term PsychologicalNon-syndromic sagittal synostosisCohen's dSecond editionSAS groupChildrenFunction outcomesWithdrawal symptomsPsychologicalAssessment systemBehavioralSkillsParentsCaregiversInventoryExecutivesWhat Is the Difference in Cranial Base Morphology in Isolated and Syndromic Bicoronal Synostosis?
Lu X, Forte AJ, Wilson AT, Park KE, Allam O, Mozaffari MA, Alperovich M, Steinbacher DM, Alonso N, Persing JA. What Is the Difference in Cranial Base Morphology in Isolated and Syndromic Bicoronal Synostosis? Plastic & Reconstructive Surgery 2020, 146: 599-610. PMID: 32842109, DOI: 10.1097/prs.0000000000007068.Peer-Reviewed Original ResearchComparison of Neurocognitive Outcomes in Postoperative Adolescents with Unilateral Coronal Synostosis.
Wu RT, Gabrick KS, Singh A, Landi N, Taylor JA, Bartlett SP, Persing JA, Alperovich M. Comparison of Neurocognitive Outcomes in Postoperative Adolescents with Unilateral Coronal Synostosis. Plastic & Reconstructive Surgery 2020, 146: 614-619. PMID: 32842112, DOI: 10.1097/prs.0000000000007067.Peer-Reviewed Original ResearchConceptsPerformance intelligence quotientVisual-motor integrationVerbal intelligence quotientIntelligence quotientMean full-scale intelligence quotientMotor integrationLeft-sided patientsRight-side patientsNonsyndromic craniosynostosisLong-term functionLarge population studiesCranial vaultHigh motor coordinationMotor achievementsUnilateral coronal synostosisFull-scale intelligence quotientIndependent predictorsFemale patientsStudy cohortNeurodevelopmental assessmentAverage intelligence quotient scoresMean ageControl subjectsNeurocognitive outcomesIntelligence quotient scoresRadiographic Predictors of FACE-Q Outcomes Following Non-Operative Orbital Floor Fracture Management.
Gabrick K, Smetona J, Iyengar R, Dinis J, Chouiari F, Peck CJ, Persing J, Alperovich M. Radiographic Predictors of FACE-Q Outcomes Following Non-Operative Orbital Floor Fracture Management. Journal Of Craniofacial Surgery 2020, 31: e388-e391. PMID: 32176015, DOI: 10.1097/scs.0000000000006356.Peer-Reviewed Original ResearchConceptsOrbital floor fracture managementOrbital floor fracturesPercent of patientsNon-operative managementPsychosocial distressFloor fracturesRadiographic findingsFracture managementMaxillary sinusYale-New Haven HospitalRight-sided fracturesAppearance-related psychosocial distressInferior rectus muscleLong-term outcomesPatient-reported questionnaireRectus muscle belliesMultiple surgical subspecialtiesNew Haven HospitalMean fracture areaBony injuriesInferior rectusOperative indicationsClinical findingsCommon injuriesMean durationCranial Fossa Development in Differing Subtypes of Crouzon Syndrome.
Lu X, Forte AJ, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Cranial Fossa Development in Differing Subtypes of Crouzon Syndrome. Journal Of Craniofacial Surgery 2020, 31: 673-677. PMID: 32049910, DOI: 10.1097/scs.0000000000006181.Peer-Reviewed Original ResearchSMAD6 Genotype Predicts Neurodevelopment in Nonsyndromic Craniosynostosis.
Wu RT, Timberlake AT, Abraham PF, Gabrick KS, Lu X, Peck CJ, Sawh-Martinez RF, Steinbacher DM, Alperovich MA, Persing JA. SMAD6 Genotype Predicts Neurodevelopment in Nonsyndromic Craniosynostosis. Plastic & Reconstructive Surgery 2020, 145: 117e-125e. PMID: 31592950, DOI: 10.1097/prs.0000000000006319.Peer-Reviewed Original ResearchMeSH KeywordsCase-Control StudiesChildChild BehaviorChild DevelopmentChild, PreschoolCraniosynostosesCraniotomyDevelopmental DisabilitiesDouble-Blind MethodFemaleFollow-Up StudiesHumansInfantIntelligence TestsLoss of Function MutationMalePlastic Surgery ProceduresProspective StudiesSkullSmad6 ProteinTreatment Outcome
2019
Cranial Fossa Volume in Differing Subtypes of Apert Syndrome.
Lu X, Forte AJ, Wilson A, Alperovich M, Steinbacher DM, Alonso N, Persing JA. Cranial Fossa Volume in Differing Subtypes of Apert Syndrome. Journal Of Craniofacial Surgery 2019, 30: 2345-2349. PMID: 31609946, DOI: 10.1097/scs.0000000000005785.Peer-Reviewed Original ResearchCleft lip repair: are outcomes between unilateral and bilateral clefts comparable?
Chouairi F, Mets EJ, Torabi SJ, Alperovich M. Cleft lip repair: are outcomes between unilateral and bilateral clefts comparable? Journal Of Plastic Surgery And Hand Surgery 2019, 54: 29-32. PMID: 31524555, DOI: 10.1080/2000656x.2019.1661848.Peer-Reviewed Original ResearchMeSH KeywordsAsthmaCardiovascular Surgical ProceduresCase-Control StudiesCentral Nervous SystemCleft LipComorbidityDatabases, FactualDevelopmental DisabilitiesFemaleGastrointestinal DiseasesHumansInfantMaleNutritional SupportPatient ReadmissionReoperationRespiration, ArtificialTracheostomyUnited StatesConceptsPeri-operative outcomesCleft lip repairMore comorbiditiesBilateral cleftsCleft lipNational Surgical Quality Improvement Program Pediatric databaseLip repairStructural central nervous system abnormalitiesCentral nervous system abnormalitiesPrimary cleft lip repairUnilateral cleft lip patientsBilateral cleft patientsPrevious cardiac surgeryPost-operative outcomesPrimary cleft lipNervous system abnormalitiesBilateral cleft lipCleft lip patientsCleft populationVentilator dependencePatient demographicsCardiac surgeryNutritional supportPropensity matchingOperative courseWhat Is the Skull Structure Influence of Squamosal Suture Synostosis in Nonsyndromic and Syndromic Crouzon Craniosynostosis?
Lu X, Chen G, Forte AJ, Cabrejo R, Singh A, Kyle G, Steinbacher DM, Alperovich M, Alonso N, Persing JA. What Is the Skull Structure Influence of Squamosal Suture Synostosis in Nonsyndromic and Syndromic Crouzon Craniosynostosis? Journal Of Craniofacial Surgery 2019, 30: 1671-1675. PMID: 30950948, DOI: 10.1097/scs.0000000000005396.Peer-Reviewed Original ResearchConceptsMiddle cranial fossaAnterior cranial fossaCranial fossaPosterior cranial fossaSquamosal synostosisFossa volumeCrouzon syndromeSquamosal suture synostosisComputed tomography scanCranial volumeNonsyndromic craniosynostosis patientsVolume reductionSevere volume reductionTomography scanNormal controlsMorphologic effectsCraniosynostosis patientsFossaPremature closureSyndromic conditionsSuture synostosisSyndromic synostosisFrankfort horizontal planeSynostosisThree-dimensional cephalometryAirway Analysis in Apert Syndrome.
Forte AJ, Lu X, Hashim PW, Steinbacher DM, Alperovich M, Persing JA, Alonso N. Airway Analysis in Apert Syndrome. Plastic & Reconstructive Surgery 2019, 144: 704-709. PMID: 31461034, DOI: 10.1097/prs.0000000000005937.Peer-Reviewed Original ResearchConceptsPosterior nasal spineApert syndromeNasal spineTomographic scanPharyngeal airway volumeRespiratory insufficiencyAirway compromiseAirway volumeAirway spaceRespiratory impairmentClinical managementAirway analysisPosterior airwayNasal cavityDisease comorbiditiesPatientsSyndromeSkull baseNasal measurementsSpine distanceStatistical significanceMidfacial deformitiesSpineAirwayPharyngeal regionPredictors of Adverse Events Following Cleft Palate Repair.
Mets EJ, Chouairi F, Torabi SJ, Alperovich M. Predictors of Adverse Events Following Cleft Palate Repair. Journal Of Craniofacial Surgery 2019, 30: 1414-1418. PMID: 31299734, DOI: 10.1097/scs.0000000000005542.Peer-Reviewed Original ResearchConceptsCleft palate repairPerioperative blood transfusionBronchopulmonary dysplasia/chronic lung diseaseAdverse eventsChronic lung diseaseBlood transfusionPalate repairRisk factorsCerebral palsyLung diseaseNational Surgical Quality Improvement Project Pediatric databasePrimary cleft palate repairWound dehiscence rateSurgical risk factorsThirty-day readmissionIntraoperative adverse eventsPost-surgical complicationsSystemic risk factorsCleft palate surgeryYears of ageLife-threatening risksReoperation rateProlonged lengthPulmonary diseaseRisk stratificationAnalysis of Airway and Midface in Crouzon Syndromes
Forte AJ, Lu X, Hashim PW, Steinbacher DM, Alperovich M, Persing JA, Alonso N. Analysis of Airway and Midface in Crouzon Syndromes. Annals Of Plastic Surgery 2019, Publish Ahead of Print: &na;. PMID: 30633021, DOI: 10.1097/sap.0000000000001740.Peer-Reviewed Original ResearchConceptsPharyngeal airway volumeComputed tomography scanAirway volumeControl subjectsTomography scanCrouzon syndromeAge-matched control subjectsAnalysis of airwaysSevere respiratory impairmentNasal airway volumePosterior pharyngeal wallEarly mixed dentitionCrouzon groupSurgical interventionRespiratory impairmentUpper airwaySoft tissue measurementsPharyngeal wallPosterior tongueMixed dentitionAirwayPatientsSyndromeVolumetric assessmentT-testAssociation of Regional Cranial Base Deformity and Ultimate Structure in Crouzon Syndrome.
Lu X, Jorge Forte A, Sawh-Martinez R, Wu R, Cabrejo R, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Association of Regional Cranial Base Deformity and Ultimate Structure in Crouzon Syndrome. Plastic & Reconstructive Surgery 2019, 143: 1233e-1243e. PMID: 31136487, DOI: 10.1097/prs.0000000000005643.Peer-Reviewed Original ResearchNational 30-Day Outcomes for Posterior Cranial Vault Distraction
Chouairi F, Torabi SJ, Alperovich M. National 30-Day Outcomes for Posterior Cranial Vault Distraction. Journal Of Craniofacial Surgery 2019, Publish Ahead of Print: &na;. PMID: 30807468, DOI: 10.1097/scs.0000000000005285.Peer-Reviewed Original ResearchConceptsPosterior vault distractionOperative timePediatric databaseNational Surgical Quality Improvement Program Pediatric databaseCalvarial volumeBlood transfusion volumeIncidence of strokeMajority of patientsSurgical site infectionPosterior cranial vault distractionNational pediatric databaseTransfusion requirementsTransfusion volumeOlder patientsPerioperative outcomesBlood transfusionPatient ageSite infectionPatient backgroundSafety profileSafe procedureRisk factorsInclusion criteriaPatient profilesPatientsMandibular Spatial Reorientation and Morphological Alteration of Crouzon and Apert Syndrome.
Lu X, Sawh-Martinez R, Forte AJ, Wu R, Cabrejo R, Wilson A, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Mandibular Spatial Reorientation and Morphological Alteration of Crouzon and Apert Syndrome. Annals Of Plastic Surgery 2019, 83: 568-582. PMID: 31008788, DOI: 10.1097/sap.0000000000001811.Peer-Reviewed Original ResearchImpact of advanced age on microvascular reconstruction of the lower facial third: An American College of Surgeons NSQIP study
Torabi SJ, Chouairi F, Dinis J, Alperovich M. Impact of advanced age on microvascular reconstruction of the lower facial third: An American College of Surgeons NSQIP study. Microsurgery 2019, 39: 487-496. PMID: 30945351, DOI: 10.1002/micr.30455.Peer-Reviewed Original ResearchConceptsMicrovascular reconstructionOperative timeNational Surgical Quality Improvement Program analysisOlder populationStandard of careImpact of ageLocal flap reconstructionLonger LOHSMore comorbiditiesNSQIP StudyHospital stayComplication rateOlder patientsPerioperative safetySubgroup analysisAdvanced ageMicrovascular flapsFlap reconstructionProcedure typeRetrospective natureAblative proceduresComparable outcomesAmerican CollegeElderly populationNeck reconstructionUnderstanding the Learning Disabilities Linked to Sagittal Craniosynostosis
Cabrejo R, Lacadie C, Brooks E, Beckett J, Sun A, Yang J, Chuang C, Eilbott J, Duncan C, Steinbacher D, Alperovich M, Ventola P, Pelphrey K, Constable T, Persing J. Understanding the Learning Disabilities Linked to Sagittal Craniosynostosis. Journal Of Craniofacial Surgery 2019, 30: 497-502. PMID: 30676447, DOI: 10.1097/scs.0000000000005194.Peer-Reviewed Original ResearchConceptsAttention deficit hyperactivity disorderFunctional magnetic resonance imagingSagittal nonsyndromic craniosynostosisSagittal craniosynostosisDifferent neural connectionsPrimary visual cortexVisual association cortexMagnetic resonance imagingStatistical parametric mappingDeficit hyperactivity disorderBrodmann area 11Association cortexVisual cortexResonance imagingNeurocognitive deficitsNeural connectionsPatientsFMRI scansHyperactivity disorderNonsyndromic craniosynostosisParametric mappingControl adolescentsAuditory processingArea 11Craniosynostosis