Michael Alperovich, MD, MSc, FACS
he/him/his
Associate Professor of Surgery (Plastic)Cards
About
Research
Publications
2026
Surgical Timing as a Marker for Developmental Diagnoses and Behavioral Therapy Utilization in Nonsyndromic Craniosynostosis.
Kong V, Salib A, Allam O, Parker E, Kauke-Navarro M, Moscarelli J, Glaeser-Khan S, Alperovich M. Surgical Timing as a Marker for Developmental Diagnoses and Behavioral Therapy Utilization in Nonsyndromic Craniosynostosis. Journal Of Craniofacial Surgery 2026 PMID: 42301239, DOI: 10.1097/scs.0000000000013054.Peer-Reviewed Original ResearchNonsyndromic craniosynostosisIndependent predictorsSurgical timeLate interventionTherapy utilizationHighest prevalenceHigh-risk cohortRetrospective cohort studyMarketScan Commercial DatabaseRetrospective natureCohort studyEarly groupNeurodevelopmental surveillanceMultilevel logistic regressionLogistic regressionPsychiatric disordersDiagnosisDevelopmental diagnosisCraniosynostosisPatientsEarly interventionDisorder prevalenceDevelopmental disorder diagnosisSession intensityPrevalenceSingle-dose subcutaneous methadone and postoperative analgesia: A case report
Plano M, Valedon A, Alperovich M, Hyman J. Single-dose subcutaneous methadone and postoperative analgesia: A case report. JCA Advances 2026, 3: 100236. DOI: 10.1016/j.jcadva.2026.100236.Peer-Reviewed Original ResearchFacial feminization surgeryFeminization surgeryRescue opioid requirementsMultimodal analgesic regimenOpioid-sparing effectDoses of oxycodoneModerate postoperative painLong duration of actionWell-controlled painPost-anesthesia care unitRoute of administrationDuration of actionAdministration of methadoneLong durationAnalgesic regimenOpioid requirementsPostoperative painOpioid usePostoperative dayAnalgesic effectSC doseUncomplicated recoveryClinical effectsPharmacokinetic dataCare unit"Soft-Tissue Response to Hard Tissue Changes Following Facial Feminization Surgery: A Three-Dimensional Region-Based Study".
Glaeser-Khan S, Rancu A, Flores Perez P, Kong V, Salib A, Lewis K, Allam O, Shen Y, Singh N, Alperovich M. "Soft-Tissue Response to Hard Tissue Changes Following Facial Feminization Surgery: A Three-Dimensional Region-Based Study". Plastic & Reconstructive Surgery 2026 PMID: 42202264, DOI: 10.1097/prs.0000000000013235.Peer-Reviewed Original ResearchDuration of hormone therapyBody mass indexFacial feminization surgerySoft tissue thicknessHormone therapyComputed tomographyFeminization surgeryBony changesTissue thicknessTissue changesHard tissue changesSoft tissue reductionSoft tissue parametersSoft tissue changesSoft tissueSoft tissue responseAesthetic outcomesBony reductionMass indexTissue reductionSurgeryAnatomical changesGonial regionMultivariate regressionAnthropometric landmarksQuantitative Assessment of Craniofacial Changes Following Facial Feminization Surgery Using Computerized Tomography Segmentation
Flores-Perez P, Rancu A, Vassallo M, Moscarelli J, Allam O, Lewis K, Mukherjee T, Alperovich M. Quantitative Assessment of Craniofacial Changes Following Facial Feminization Surgery Using Computerized Tomography Segmentation. Transgender Health 2026 DOI: 10.1177/26884887261450318.Peer-Reviewed Original ResearchFacial feminization surgeryGonial angleComputed tomographyFeminization surgeryCraniofacial changesPostoperative CT scansChin volumeCT segmentationChin projectionEighty patientsPaired t-testCT scanPostoperative measurementsAcademic medical centerAssessment of outcomesAngle morphologySkeletal changesFrontonasal angleMedical CenterMimics softwareChinSurgeryQuantitative assessmentForeheadPatientsLong-Term Intracranial and Ophthalmologic Outcomes in Single Suture Craniosynostosis.
Salib A, Kong V, Glaeser-Khan S, Allam O, Alperovich M. Long-Term Intracranial and Ophthalmologic Outcomes in Single Suture Craniosynostosis. Journal Of Craniofacial Surgery 2026 PMID: 42153715, DOI: 10.1097/scs.0000000000012895.Peer-Reviewed Original ResearchElevated intracranial pressureSingle suture craniosynostosisPediatric Health Information SystemIntracranial pressureSuture craniosynostosisOphthalmological outcomesUnicoronal synostosisAssociated with elevated intracranial pressureLong-term postoperative surveillanceSuture typeChiari I malformationRetrospective cohort studyShort follow-upMultivariate logistic regressionSingle-suture craniosynostosisGenetic comorbiditiesIntracranial morbidityOphthalmological sequelaeSurgical ageOphthalmologic complicationsChiari malformationPostoperative surveillanceLambdoid synostosisSurgical correctionSurgical timeEvolving Trends in Perioperative Pain Management for Pediatric Patients Undergoing Cranial Vault Remodeling and Strip Craniectomy.
Salib A, Bai W, Kong V, Glaeser-Khan S, Allam O, Goss J, Alperovich M. Evolving Trends in Perioperative Pain Management for Pediatric Patients Undergoing Cranial Vault Remodeling and Strip Craniectomy. Journal Of Craniofacial Surgery 2026 PMID: 42149738, DOI: 10.1097/scs.0000000000012943.Peer-Reviewed Original ResearchCranial vault remodelingMorphine Milligram EquivalentsPediatric Health Information SystemPerioperative pain managementStrip craniectomyAnalgesic utilizationOpioid exposureOpioid utilizationCraniosynostosis surgeryVault remodelingPain managementDaily morphine milligram equivalentsPediatric craniosynostosis surgeryRetrospective cohort studyMilligram equivalentsOpioid administrationOpioid usePediatric patientsAcetaminophen useBetween-group differencesAnalgesic administrationCraniosynostosis patientsSurgical techniqueCohort studyOpioidEthical Implementations of Artificial Intelligence in Craniofacial and Facial Plastic Surgery
Allam O, Kong V, Alperovich M. Ethical Implementations of Artificial Intelligence in Craniofacial and Facial Plastic Surgery. Journal Of Craniofacial Surgery 2026, 37: 1412-1415. PMID: 42113018, DOI: 10.1097/scs.0000000000012862.Peer-Reviewed Original ResearchPredictors of New-Onset Anxiety or Depression Following Open Reduction and Internal Fixation of Mandible Fractures.
Salib A, Kong V, Bai W, Allam O, Grauer J, Alperovich M. Predictors of New-Onset Anxiety or Depression Following Open Reduction and Internal Fixation of Mandible Fractures. Journal Of Oral And Maxillofacial Surgery 2026 PMID: 42167351, DOI: 10.1016/j.joms.2026.04.021.Peer-Reviewed Original ResearchMandible fracturesCharlson Comorbidity IndexHealing complicationsInternal fixationOpen reductionInternal fixation of mandible fracturesFemale sexComorbidity indexFixation of mandible fracturesFunctional impairmentICD-9/10Relative riskAnxiety diagnosesDays of follow-upIsolated mandible fracturesNational insurance claims databaseTreated with ORIFHigher Charlson comorbidity indexInternational ClassificationTemporomandibular joint ankylosisRetrospective cohort studyMultivariate logistic regression modelAssociated with higher ratesSubstance useICD-9/10 codesPatient satisfaction following gender affirming facial surgery: a GENDER-Q and gender preoccupation and stability questionnaire study (GPSQ)
Hosseini H, Mukherjee T, Flores-Perez P, Vassallo M, Ihnat J, Wood S, Hu K, Parikh N, Allam O, Alperovich M. Patient satisfaction following gender affirming facial surgery: a GENDER-Q and gender preoccupation and stability questionnaire study (GPSQ). Journal Of Patient-Reported Outcomes 2026, 10: 106. PMID: 42082789, DOI: 10.1186/s41687-026-01016-1.Peer-Reviewed Original ResearchConceptsPatient-reported outcome measuresPre-to post-operative changesFacial surgeryUpper facial thirdPre- and post-operative outcomesPost-operative outcomesFacial satisfactionUnpaired t-testGender-affirming surgeryFacial thirdSpearman correlation coefficientGender dysphoriaFacial harmonySurgerySubunit changesPopulation-specific interventionsResultsSignificant improvementsScore improvementPatient satisfactionPatientsTransgender patientsOutcome measuresUpper faceChinFacial featuresAge at Surgery Associated With Increased Expressive Language Delays in Children With Single Suture Craniosynostosis
Salib A, Hu K, Pérez P, Rancu A, Allam O, Bach K, Kong V, Moscarelli J, Chapman E, Alperovich M. Age at Surgery Associated With Increased Expressive Language Delays in Children With Single Suture Craniosynostosis. Journal Of Craniofacial Surgery 2026, 37: 2020-2024. PMID: 42012008, DOI: 10.1097/scs.0000000000012775.Peer-Reviewed Original ResearchRetrospective cohort studySingle-suture craniosynostosisAssociated with higher oddsRetrospective cohort study of patientsExpressive language delayCohort study of patientsSuture typeStudy of patientsAssociated with higher ratesSingle suture craniosynostosisMultivariate logistic regressionElevated burdenCleft palateHearing lossLanguage delaySyndromic craniosynostosisCraniosynostosis patientsSuture craniosynostosisGenetic syndromesSurgeryAcademic centersCraniosynostosisPatientsInclusion criteriaLogistic regression
Academic Achievements & Community Involvement
Clinical Care
Overview
Michael Alperovich, MD, MSc, FACS, is a plastic surgeon with a focus on reconstructive and aesthetic surgery for the face, breast, and body. As Co-Director of Craniofacial Surgery at Yale, Dr. Alperovich has specialized training in congenital craniofacial surgery conditions, including cleft lip and palate, craniosynostosis, mandibular distraction, and ear reconstruction. Dr. Alperovich has expertise in facial aesthetic surgery including facelift, otoplasty, facial fat grafting, rhinoplasty, and blepharoplasty. Dr. Alperovich also regularly performs breast and body aesthetic surgery including breast lift, abdominoplasty, liposuction, and fat grafting.
When meeting a new patient, Dr. Alperovich says his goal is to provide a surgery that will maximize the patient’s quality of life by restoring or recreating appearance and function to the best possible state. “I promise every patient that once I start a reconstructive or aesthetic procedure, I will keep working with them until they are satisfied,” he says.
He finds his work to be invigorating on a daily basis. “As a plastic surgeon, I have the privilege of being one of the few types of doctors that patients look forward to seeing,” Dr. Alperovich says. “The best part of my job is having the chance help a patient during a time of need and to serve as a positive, uplifting part of what can be a trying chapter.”
Dr. Alperovich is an associate professor of surgery (plastics division) at Yale School of Medicine. He is the recipient of multiple institutional and national awards including the CRANIO award by the American Society of Maxillofacial Surgeons and Yale Department of Surgery Academic Development Award. He has been an invited visiting professor and guest speaker nationally and internationally, authored multiple book chapters, published over 100 peer-reviewed publications, and serves on the editorial boards of several plastic surgery journals.
Clinical Specialties
Craniofacial Surgery; Plastic & Reconstructive Surgery; Pediatric Surgery
Fact Sheets
Congenital Deformities of the Outer Ear
Learn More on Yale MedicineAesthetic Plastic Surgery
Learn More on Yale MedicineSurgery for Cleft Lip and Palate
Learn More on Yale MedicineReproductive Options for Transgender Individuals
Learn More on Yale Medicine
Board Certifications
Plastic Surgery
- Certification Organization
- AB of Plastic Surgery
- Original Certification Date
- 2017
Yale Medicine News
News & Links
News
- May 28, 2026
Yale Surgery Announces 2026 Transformational Educators Honor Roll
- May 02, 2024
Yale Surgeons Recognized by Connecticut Magazine's 2024 “Top Doctors” List
- May 01, 2023
Connecticut Magazine’s 2023 “Top Doctors” issue recognizes 81 Smilow Cancer Hospital and Yale Cancer Center physicians
- September 28, 2022Source: Yale Medicine
Microsurgery: What You Need To Know
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Plastic & Reconstructive Surgery
330 Cedar Street, PO Box 208062
New Haven, CT 06520-8062
United States
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