2020
Surgical Outcomes of Mastectomy with Immediate Autologous Reconstruction Followed by Radiation
Heller DR, Zhuo H, Zhang Y, Parikh N, Fusi S, Alperovich M, Lannin DR, Higgins SA, Avraham T, Killelea BK. Surgical Outcomes of Mastectomy with Immediate Autologous Reconstruction Followed by Radiation. Annals Of Surgical Oncology 2020, 28: 2169-2179. PMID: 32974699, DOI: 10.1245/s10434-020-09122-0.Peer-Reviewed Original ResearchConceptsPostmastectomy radiation therapyLarge institutional cohortProbability of complicationsImmediate autologous reconstructionAutologous reconstructionMultivariable analysisInstitutional cohortFlap outcomesRadiation-related complicationsRisk of complicationsChest wall asymmetryMethodsMedical recordsNodal radiationMedian followNeoadjuvant chemotherapyPrimary endpointResultsOne hundredSurgical outcomesFat necrosisFlap complicationsImmediate reconstructionReoperationRadiation therapyComplicationsFat graftingComparison of Neurocognitive Outcomes in Postoperative Adolescents with Unilateral Coronal Synostosis.
Wu RT, Gabrick KS, Singh A, Landi N, Taylor JA, Bartlett SP, Persing JA, Alperovich M. Comparison of Neurocognitive Outcomes in Postoperative Adolescents with Unilateral Coronal Synostosis. Plastic & Reconstructive Surgery 2020, 146: 614-619. PMID: 32842112, DOI: 10.1097/prs.0000000000007067.Peer-Reviewed Original ResearchConceptsPerformance intelligence quotientVisual-motor integrationVerbal intelligence quotientIntelligence quotientMean full-scale intelligence quotientMotor integrationLeft-sided patientsRight-side patientsNonsyndromic craniosynostosisLong-term functionLarge population studiesCranial vaultHigh motor coordinationMotor achievementsUnilateral coronal synostosisFull-scale intelligence quotientIndependent predictorsFemale patientsStudy cohortNeurodevelopmental assessmentAverage intelligence quotient scoresMean ageControl subjectsNeurocognitive outcomesIntelligence quotient scoresSMAD6 Genotype Predicts Neurodevelopment in Nonsyndromic Craniosynostosis.
Wu RT, Timberlake AT, Abraham PF, Gabrick KS, Lu X, Peck CJ, Sawh-Martinez RF, Steinbacher DM, Alperovich MA, Persing JA. SMAD6 Genotype Predicts Neurodevelopment in Nonsyndromic Craniosynostosis. Plastic & Reconstructive Surgery 2020, 145: 117e-125e. PMID: 31592950, DOI: 10.1097/prs.0000000000006319.Peer-Reviewed Original ResearchMeSH KeywordsCase-Control StudiesChildChild BehaviorChild DevelopmentChild, PreschoolCraniosynostosesCraniotomyDevelopmental DisabilitiesDouble-Blind MethodFemaleFollow-Up StudiesHumansInfantIntelligence TestsLoss of Function MutationMalePlastic Surgery ProceduresProspective StudiesSkullSmad6 ProteinTreatment Outcome
2016
“Breast in a Day”
Choi M, Frey JD, Alperovich M, Levine JP, Karp NS. “Breast in a Day”. Plastic & Reconstructive Surgery 2016, 138: 184e-191e. PMID: 27465178, DOI: 10.1097/prs.0000000000002333.Peer-Reviewed Original ResearchConceptsPermanent implant reconstructionNipple-sparing mastectomyMastectomy flap necrosisImplant reconstructionAcellular dermal matrixComplication rateFlap necrosisMajor mastectomy flap necrosisMinor mastectomy flap necrosisDermal matrixImplant sizeCLINICAL QUESTION/LEVELPercent of reconstructionsCommon major complicationPrior radiation therapyGreater complication rateLow complication rateNipple-sparing mastectomiesBody mass indexCommon minor complicationAverage implant sizeMajority of implantsOverall complicationsNipple necrosisMinor complicationsApplying Craniofacial Principles to Neurosurgical Exposures in Cerebrovascular Aneurysm Repair
Alperovich M, Frey JD, Potts MB, Riina HA, Staffenberg DA. Applying Craniofacial Principles to Neurosurgical Exposures in Cerebrovascular Aneurysm Repair. Journal Of Craniofacial Surgery 2016, 27: 1077-1079. PMID: 27192638, DOI: 10.1097/scs.0000000000002643.Peer-Reviewed Original ResearchConceptsCraniofacial principlesNeurosurgical exposureCraniofacial surgeonsZygomaticomaxillary complex fracturesSuperior cosmetic resultsAnterior skull baseRisk of injuryAneurysm repairNerve transectionCosmetic resultsFacial nerveEyebrow incisionPeriorbital surgeryFrontal branchSkull baseConspicuous scarringTranspalpebral approachComplex fracturesNeurosurgical literatureSeries experienceSurgeonsCraniofacial surgerySurgeryCraniotomyExposure
2015
Cost Analysis of Intraoperative Subareolar Frozen Section During Nipple-Sparing Mastectomy
Alperovich M, Reis SM, Choi M, Karp NS, Frey JD, Chang JB, Axelrod DM, Shapiro RL, Guth AA. Cost Analysis of Intraoperative Subareolar Frozen Section During Nipple-Sparing Mastectomy. Annals Of Surgical Oncology 2015, 23: 490-493. PMID: 26438436, DOI: 10.1245/s10434-015-4882-8.Peer-Reviewed Original ResearchConceptsIntraoperative frozen sectionSubareolar biopsyNipple-areolar complexFrozen sectionsOperating roomNipple-sparing mastectomyOccult cancerOperative resectionHealthcare chargesPathology resultsBiopsyPatient recordsFirst cost analysisRoutine useEarly detectionInstitutional frequencyMastectomyBreastCost analysisFinancial charges
2014
Nipple-Sparing Mastectomy in Patients with Prior Breast Irradiation
Alperovich M, Choi M, Frey JD, Lee ZH, Levine JP, Saadeh PB, Shapiro RL, Axelrod DM, Guth AA, Karp NS. Nipple-Sparing Mastectomy in Patients with Prior Breast Irradiation. Plastic & Reconstructive Surgery 2014, 134: 202e-206e. PMID: 25068341, DOI: 10.1097/prs.0000000000000321.Peer-Reviewed Original ResearchConceptsNipple-sparing mastectomyNipple-areola complex necrosisPrior breast irradiationMastectomy flap necrosisHigh-risk procedureBreast irradiationFlap necrosisComplete nipple-areola complex necrosisNipple-sparing mastectomy patientsHigh-risk patientsBody mass indexLatissimus dorsi flapMicrovascular free flapsSignificant differencesMastectomy cohortComplex complicationsImplant explantationMass indexMastectomy patientsCapsular contracturePartial necrosisAutologous reconstructionComplete necrosisIrradiated groupFree flap
2013
Nipple-Sparing Mastectomy in Patients with a History of Reduction Mammaplasty or Mastopexy
Alperovich M, Tanna N, Samra F, Blechman KM, Shapiro RL, Guth AA, Axelrod DM, Choi M, Karp NS. Nipple-Sparing Mastectomy in Patients with a History of Reduction Mammaplasty or Mastopexy. Plastic & Reconstructive Surgery 2013, 131: 962-967. PMID: 23629078, DOI: 10.1097/prs.0b013e3182865ad2.Peer-Reviewed Original ResearchConceptsNipple-sparing mastectomyAuthors' institutionMean body mass indexCLINICAL QUESTION/LEVELMastectomy flap necrosisSubset of patientsNipple-sparing mastectomiesBody mass indexBreast cancer recurrenceLatissimus dorsi flapPresence of cancerNipple-areola complexMass indexProphylactic indicationsFlap necrosisMean agePatient populationBiopsy resultsMastectomy patientsTherapeutic resectionCancer recurrenceNipple viabilityReconstructive outcomesMastectomyReduction mammaplasty