Mechanisms of Aortic Dissection: From Pathological Changes to Experimental and In Silico Models
Rolf-Pissarczyk M, Schussnig R, Fries T, Fleischmann D, Elefteriades J, Humphrey J, Holzapfel G. Mechanisms of Aortic Dissection: From Pathological Changes to Experimental and In Silico Models. Progress In Materials Science 2024, 101363. DOI: 10.1016/j.pmatsci.2024.101363.Peer-Reviewed Original ResearchHemodynamics and Wall Mechanics of Vascular Graft Failure
Szafron J, Heng E, Boyd J, Humphrey J, Marsden A. Hemodynamics and Wall Mechanics of Vascular Graft Failure. Arteriosclerosis Thrombosis And Vascular Biology 2024, 44: 1065-1085. PMID: 38572650, PMCID: PMC11043008, DOI: 10.1161/atvbaha.123.318239.Peer-Reviewed Original ResearchConceptsVascular graftsTissue-engineered vascular graftsWall mechanicsSolid mechanicsVascular graft failureLoad magnitudeMechanobiological processesLoadMechanobiological stimuliMechanosensitive signaling pathwaysBiomechanical stateWallGraft failureBiomechanical loadingCongenital heart surgeryCoronary artery bypass graftingEnd-organ dysfunctionGraft materialArtery bypass graftingFeedback loopComputational tools