Hitten Zaveri, PhD

There are two aspects to our work on epilepsy. First, we seek to understand, through experiments and analysis, how seizures the seemingly random disruption of brain function, are generated and how they spread through the brain. Second, we are developing brain implantable devices to sense, analyze and control aberrant brain activity. These devices include a wireless, battery-free, multimodal intracranial sensor to continuously monitor brain neurochemistry and electrophysiology (see the image on this page) and devices to detect and predict the onset of a seizure and intervene to terminate a seizure once it has been detected or predicted. Further information on our research can be found in our publications. A few, recent, publications are listed below. A comprehensive listing of our publications can be found on the Yale CNL website.

• Understand how seizures are generated
• Develop implantable multimodal sensors for direct brain sensing
• Accurately locate the seizure onset area
• Detect and predict the onset of seizures in real-time
• Develop interventional methods to terminate or abort seizures