2022
Ghrelin Predicts Stimulant and Sedative Effects of Alcohol in Heavy Drinkers
Ralevski E, Horvath T, Shanabrough M, Newcomb J, Pisani E, Petrakis I. Ghrelin Predicts Stimulant and Sedative Effects of Alcohol in Heavy Drinkers. Alcohol And Alcoholism 2022, 58: 100-106. PMID: 36382470, PMCID: PMC9830489, DOI: 10.1093/alcalc/agac058.Peer-Reviewed Original Research
2017
Ghrelin is Related to Personality Differences in Reward Sensitivity and Impulsivity
Ralevski E, Shanabrough M, Newcomb J, Gandelman E, Hayden R, Horvath TL, Petrakis I. Ghrelin is Related to Personality Differences in Reward Sensitivity and Impulsivity. Alcohol And Alcoholism 2017, 53: 52-56. PMID: 29136100, DOI: 10.1093/alcalc/agx082.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcohol DrinkingFemaleGhrelinHumansImpulsive BehaviorMalePersonalityPersonality TestsRewardSocioeconomic FactorsYoung AdultConceptsAspects of impulsivityTraits of impulsivityHealthy social drinkersSocial drinkersReward sensitivityImpulsivity traitsPersonality measuresPersonality differencesImpulsivityDrugs of abusePersonality characteristicsSubjective effectsDirect relationshipHigh levelsDrinkersFeeding-related peptidesPunishmentFirst studyIndividualsTraitsSecondary analysisParticipantsAbuseRelationshipOriginal study
2012
Reward Aspects of Gastrointestinal Hormones Mediated by Brain G Protein–Coupled Receptors
Koch M, Horvath TL. Reward Aspects of Gastrointestinal Hormones Mediated by Brain G Protein–Coupled Receptors. Biological Psychiatry 2012, 72: 340-342. PMID: 22872010, DOI: 10.1016/j.biopsych.2012.06.031.Peer-Reviewed Original Research
2002
Uncoupling protein 2 (UCP2) lowers alcohol sensitivity and pain threshold
Horvath B, Spies C, Horvath G, Kox WJ, Miyamoto S, Barry S, Warden CH, Bechmann I, Diano S, Heemskerk J, Horvath TL. Uncoupling protein 2 (UCP2) lowers alcohol sensitivity and pain threshold. Biochemical Pharmacology 2002, 64: 369-374. PMID: 12147287, DOI: 10.1016/s0006-2952(02)01167-x.Peer-Reviewed Original ResearchConceptsCentral nervous systemTemperature sensationNervous systemBasal forebrain areasMajor risk factorAcute ethanol exposureAcute alcohol consumptionImpairment of painPeripheral energy expenditureAbuse of ethanolProtein 2Ethanol-induced toleranceWild-type animalsUCP2 knockoutPain thresholdTime of recoveryInduces toleranceRisk factorsEthanol exposureForebrain areasAxon terminalsNeuronal responsesAcute exposureAlcohol consumptionEnergy homeostasis