DIPG-33. BIOLOGICAL CHARACTERIZATION OF PPM1D MUTATIONS IN THE CONTEXT OF DIPG
Fons N, Sundaram R, Surovtseva Y, Rusin S, Kettenbach A, Breuer G, Bindra R. DIPG-33. BIOLOGICAL CHARACTERIZATION OF PPM1D MUTATIONS IN THE CONTEXT OF DIPG. Neuro-Oncology 2017, 19: iv12-iv12. PMCID: PMC5475004, DOI: 10.1093/neuonc/nox083.048.Peer-Reviewed Original ResearchDNA damage response networkDNA damage response proteinsDamage response proteinsRecent genomic analysesProtein phosphataseFirst cell lineGenomic analysisResponse proteinsMolecular basisKey proteinsDiffuse intrinsic pontine gliomaDiverse arrayMutant astrocytesOncogenic potentialResponse networkBasal activationMutationsTruncating alterationsAlternative roleProtein expressionCell linesBiological characterizationTruncating mutationsPPM1DNovel list