Featured Publications
Cross-Scale Integrin Regulation Organizes ECM and Tissue Topology
Jülich D, Cobb G, Melo AM, McMillen P, Lawton AK, Mochrie SG, Rhoades E, Holley SA. Cross-Scale Integrin Regulation Organizes ECM and Tissue Topology. Developmental Cell 2015, 34: 33-44. PMID: 26096733, PMCID: PMC4496283, DOI: 10.1016/j.devcel.2015.05.005.Peer-Reviewed Original ResearchConceptsExtracellular matrixCadherin-2Integrin α5Cell-cell adhesionFluorescence cross-correlation spectroscopyECM protein fibronectinSomite boundariesCross-correlation spectroscopyAdjacent cell membranesBody elongationECM assemblyIntegrin associationIntegrin activationPhysical associationActive conformationFibronectin fibrillogenesisProtein fibronectinTissue assemblyIntegrin conformationTissue topologyInactive integrinsCell membraneCross-scale mechanismsStereotypic patternAnimal tissues
2023
Highly specific and non-invasive imaging of Piezo1-dependent activity across scales using GenEPi
Yaganoglu S, Kalyviotis K, Vagena-Pantoula C, Jülich D, Gaub B, Welling M, Lopes T, Lachowski D, Tang S, Del Rio Hernandez A, Salem V, Müller D, Holley S, Vermot J, Shi J, Helassa N, Török K, Pantazis P. Highly specific and non-invasive imaging of Piezo1-dependent activity across scales using GenEPi. Nature Communications 2023, 14: 4352. PMID: 37468521, PMCID: PMC10356793, DOI: 10.1038/s41467-023-40134-y.Peer-Reviewed Original Research