2021
Systematic review of structural and functional neuroimaging studies of cannabis use in adolescence and emerging adulthood: evidence from 90 studies and 9441 participants
Lichenstein SD, Manco N, Cope LM, Egbo L, Garrison KA, Hardee J, Hillmer AT, Reeder K, Stern EF, Worhunsky P, Yip SW. Systematic review of structural and functional neuroimaging studies of cannabis use in adolescence and emerging adulthood: evidence from 90 studies and 9441 participants. Neuropsychopharmacology 2021, 47: 1000-1028. PMID: 34839363, PMCID: PMC8938408, DOI: 10.1038/s41386-021-01226-9.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsAdolescent cannabis usersCannabis-related harmsCannabis usersCannabis effectsAdolescent brain functionOngoing brain developmentFunctional neuroimaging studiesEffects of cannabisAdolescent brainNeuroimaging studiesNeural effectsPotential moderatorsNeural alterationsCannabis policy changesReduced perceptionSystematic reviewCannabis useCerebellar regionsAdolescenceBrain functionPreliminary evidenceFuture researchEarly interventionLong-term goalExtant literature
2019
Connectome-Based Prediction of Cocaine Abstinence
Yip SW, Scheinost D, Potenza MN, Carroll KM. Connectome-Based Prediction of Cocaine Abstinence. American Journal Of Psychiatry 2019, 176: 156-164. PMID: 30606049, PMCID: PMC6481181, DOI: 10.1176/appi.ajp.2018.17101147.Peer-Reviewed Original ResearchMeSH KeywordsAdultBehavior TherapyBrainCholinesterase InhibitorsCocaine-Related DisordersCognitionConnectomeExecutive FunctionFemaleFunctional NeuroimagingGalantamineHumansIndividualityMachine LearningMagnetic Resonance ImagingMaleMiddle AgedNeural PathwaysOpiate Substitution TreatmentOpioid-Related DisordersPrognosisRewardTreatment OutcomeConceptsConnectome-based predictive modelingCocaine use disorderUse disordersBrain-based predictorsLarge-scale neural networksFunctional MRI dataCocaine abstinenceExecutive controlReward responsivenessIndividual differencesBaseline cocaine usePosttreatment assessmentConnectivity strengthHeterogeneous sampleAbstinenceIndependent samplesNovel interventionsCanonical networksSpecific behaviorsCocaine useSignificant correspondenceDisordersTreatment outcomesNetwork strengthMRI data
2014
Hypoactivation of the Ventral and Dorsal Striatum During Reward and Loss Anticipation in Antipsychotic and Mood Stabilizer-Naive Bipolar Disorder
Yip SW, Worhunsky PD, Rogers RD, Goodwin GM. Hypoactivation of the Ventral and Dorsal Striatum During Reward and Loss Anticipation in Antipsychotic and Mood Stabilizer-Naive Bipolar Disorder. Neuropsychopharmacology 2014, 40: 658-666. PMID: 25139065, PMCID: PMC4289954, DOI: 10.1038/npp.2014.215.Peer-Reviewed Original ResearchMeSH KeywordsAnticipation, PsychologicalBipolar DisorderCase-Control StudiesCorpus StriatumFemaleFunctional NeuroimagingHumansMagnetic Resonance ImagingMaleRewardYoung AdultConceptsDorsal striatumUnmedicated individualsLoss anticipationPotential ameliorative effectsAddiction-related disordersBipolar disorder IReward processingMonetary incentive delay taskSmall volume correctionFunctional magnetic resonanceIncentive delay taskAntipsychotic medicationVentral striatal activityHealthy comparison individualsPutamen volumeBipolar disorderBD-IIAmeliorative effectMedicated individualsStriatal activityDisorder IStriatumGroup comparisonsNeural activationReward anticipation
2013
Cortical glutathione levels in young people with bipolar disorder: a pilot study using magnetic resonance spectroscopy
Godlewska BR, Yip SW, Near J, Goodwin GM, Cowen PJ. Cortical glutathione levels in young people with bipolar disorder: a pilot study using magnetic resonance spectroscopy. Psychopharmacology 2013, 231: 327-332. PMID: 23955702, DOI: 10.1007/s00213-013-3244-0.Peer-Reviewed Original ResearchConceptsBipolar disorderGSH levelsOccipital cortexHealthy age-matched controlsPilot studyDSM-IV bipolar disorderPost-mortem brain tissueConclusionsThis pilot studyAge-matched controlsProton magnetic resonance spectroscopyTime of studyMagnetic resonance spectroscopyCortical GSHIll patientsCortical metabolitesΓ-aminobutyric acidCellular free radicalsMood disturbanceUseful biomarkerBipolar pathophysiologyPatientsTrait biomarkerBrain tissueGlutathione levelsObjectivesThe objective