2023
Developing Validated Tools to Identify Pulmonary Embolism in Electronic Databases: Rationale and Design of the PE-EHR+ Study
Bikdeli B, Lo Y, Khairani C, Bejjani A, Jimenez D, Barco S, Mahajan S, Caraballo C, Secemsky E, Klok F, Hunsaker A, Aghayev A, Muriel A, Wang Y, Hussain M, Appah-Sampong A, Lu Y, Lin Z, Aneja S, Khera R, Goldhaber S, Zhou L, Monreal M, Krumholz H, Piazza G. Developing Validated Tools to Identify Pulmonary Embolism in Electronic Databases: Rationale and Design of the PE-EHR+ Study. Thrombosis And Haemostasis 2023, 123: 649-662. PMID: 36809777, PMCID: PMC11200175, DOI: 10.1055/a-2039-3222.Peer-Reviewed Original ResearchConceptsElectronic health recordsNLP algorithmNatural language processing toolsLanguage processing toolsPrincipal discharge diagnosisICD-10 codesDischarge diagnosisNLP toolsChart reviewHealth systemProcessing toolsYale New Haven Health SystemPatient identificationElectronic databasesHealth recordsData validationHigh-risk PEPulmonary Embolism ResearchSecondary discharge diagnosisIdentification of patientsManual chart reviewNegative predictive valueCodeRadiology reportsAlgorithm
2015
Role of D-dimer Assays in the Diagnostic Evaluation of Pulmonary Embolism
Jain S, Khera R, Suneja M, Gehlbach B, Kuperman E, Lopez F. Role of D-dimer Assays in the Diagnostic Evaluation of Pulmonary Embolism. The American Journal Of The Medical Sciences 2015, 350: 501-507. PMID: 25719981, DOI: 10.1097/maj.0000000000000405.Peer-Reviewed Original ResearchMeSH KeywordsAgedDiagnosis, DifferentialFibrin Fibrinogen Degradation ProductsHumansMalePneumoniaPredictive Value of TestsPulmonary EmbolismConceptsDiagnosis of PEPulmonary embolismClinical featuresD-dimerDiagnostic algorithmPositive D-dimer testNonspecific clinical featuresSimple noninvasive testD-dimer testD-dimer assayClinician suspicionInitial imagingAlternative diagnosesElderly menNoninvasive testsClinical algorithmDiagnostic evaluationChest imagingDiagnosisEmbolismLittle valueImagingComorbiditiesPneumoniaPatients