2018
Managing Implantable Cardioverter-Defibrillators at End-of-Life: Practical Challenges and Care Considerations
Khera R, Pandey A, Link MS, Sulistio MS. Managing Implantable Cardioverter-Defibrillators at End-of-Life: Practical Challenges and Care Considerations. The American Journal Of The Medical Sciences 2018, 357: 143-150. PMID: 30665495, DOI: 10.1016/j.amjms.2018.11.016.Peer-Reviewed Original ResearchConceptsManagement of ICDsLife-saving therapyImplantable cardioverter defibrillatorFinal common pathwayPatient-centered approachICD shocksCardiopulmonary arrestMalignant arrhythmiasPalliative carePatient deathCare considerationsCardioverter defibrillatorLife carePatient's lifeAppropriate managementMedical interventionsICDCommon pathwayNatural deathPatientsDeathNumber of peopleCarePainArrhythmias
2016
Comparative Effectiveness of Pharmacologic Interventions for Pulmonary Arterial Hypertension A Systematic Review and Network Meta-Analysis
Jain S, Khera R, Girotra S, Badesch D, Wang Z, Murad MH, Blevins A, Schmidt GA, Singh S, Gerke AK. Comparative Effectiveness of Pharmacologic Interventions for Pulmonary Arterial Hypertension A Systematic Review and Network Meta-Analysis. CHEST Journal 2016, 151: 90-105. PMID: 27615023, PMCID: PMC5310124, DOI: 10.1016/j.chest.2016.08.1461.Peer-Reviewed Original ResearchConceptsPulmonary arterial hypertensionEndothelin receptor antagonistsArterial hypertensionPharmacologic interventionsFunctional statusNew York Heart Association/World Health Organization functional classWorld Health Organization functional classSystematic reviewFuture comparative-effectiveness trialDiscontinuation of therapyA Systematic ReviewComparative effectiveness trialNetwork Meta-AnalysisPatient-centered approachClinical worseningCochrane RegisterSubcutaneous prostanoidsEfficacy outcomesPlacebo groupPlacebo ratesAdverse eventsReceptor antagonistPharmacologic agentsEffectiveness trialComparative efficacy