2023
Validation of the European SCORE2 models in a Canadian primary care cohort
Sud M, Sivaswamy A, Austin P, Abdel-Qadir H, Anderson T, Khera R, Naimark D, Lee D, Roifman I, Thanassoulis G, Tu K, Wijeysundera H, Ko D. Validation of the European SCORE2 models in a Canadian primary care cohort. European Journal Of Preventive Cardiology 2023, 31: 668-676. PMID: 37946603, PMCID: PMC11025037, DOI: 10.1093/eurjpc/zwad352.Peer-Reviewed Original ResearchPrimary care cohortAtherosclerotic cardiovascular diseaseLow-risk regionsCare cohortC-statisticOlder personsElectronic medical record dataLarge Canadian cohortMedical record dataYears of ageYoung personASCVD riskCanadian cohortCardiovascular diseaseOlder womenIndividuals 70Age groupsSCORE2CohortRecord dataWomenMenRiskPersonsDisease
2018
Readmissions of adults within three age groups following hospitalization for pneumonia: Analysis from the Nationwide Readmissions Database
Jain S, Khera R, Mortensen EM, Weissler JC. Readmissions of adults within three age groups following hospitalization for pneumonia: Analysis from the Nationwide Readmissions Database. PLOS ONE 2018, 13: e0203375. PMID: 30212485, PMCID: PMC6136736, DOI: 10.1371/journal.pone.0203375.Peer-Reviewed Original ResearchConceptsMiddle-aged adultsNationwide Readmissions DatabaseAge groupsPneumonia readmissionsIndex pneumonia hospitalizationPatterns of readmissionRate of readmissionRisk-adjusted analysisMultivariable regression modelsYears of ageRisk-adjustment modelsPneumonia hospitalizationsReadmission ratesPrimary diagnosisHigh burdenReadmissionReadmission eventsHospitalizationMean costInsurance payerPneumoniaPotential interventionsYoung adultsAdultsSubstantial rateTrends in 30-Day Readmission Rates for Medicare and Non-Medicare Patients in the Era of the Affordable Care Act
Angraal S, Khera R, Zhou S, Wang Y, Lin Z, Dharmarajan K, Desai NR, Bernheim SM, Drye EE, Nasir K, Horwitz LI, Krumholz HM. Trends in 30-Day Readmission Rates for Medicare and Non-Medicare Patients in the Era of the Affordable Care Act. The American Journal Of Medicine 2018, 131: 1324-1331.e14. PMID: 30016636, PMCID: PMC6380174, DOI: 10.1016/j.amjmed.2018.06.013.Peer-Reviewed Original ResearchConceptsHospital Readmissions Reduction ProgramReadmission ratesAcute myocardial infarctionHeart failurePatient groupMyocardial infarctionCause readmission rateNationwide Readmissions DatabaseReadmissions Reduction ProgramNon-Medicare patientsNon-target conditionsLower readmissionAffordable Care ActMedicare beneficiariesAge groupsPrivate insuranceCare ActPneumoniaInfarctionPatientsReduction programsMedicareGroupReadmissionFailureImpact of 2017 ACC/AHA guidelines on prevalence of hypertension and eligibility for antihypertensive treatment in United States and China: nationally representative cross sectional study
Khera R, Lu Y, Lu J, Saxena A, Nasir K, Jiang L, Krumholz HM. Impact of 2017 ACC/AHA guidelines on prevalence of hypertension and eligibility for antihypertensive treatment in United States and China: nationally representative cross sectional study. The BMJ 2018, 362: k2357. PMID: 29997129, PMCID: PMC6039831, DOI: 10.1136/bmj.k2357.Peer-Reviewed Original ResearchConceptsACC/AHA guidelinesDiagnosis of hypertensionAge groupsHypertension guidelinesAHA guidelinesTreatment patternsCurrent guidelinesACC/AHA hypertension guidelinesHeart Association hypertension guidelinesCurrent treatment patternsIntensification of treatmentPrevalence of hypertensionNutrition Examination SurveyYears age groupUS National HealthYear old adultsSame age groupRetirement Longitudinal StudyAntihypertensive treatmentExamination SurveyNational HealthHypertensionAmerican CollegeChina HealthOlder adults
2017
Comparison of Readmission Rates After Acute Myocardial Infarction in 3 Patient Age Groups (18 to 44, 45 to 64, and ≥65 Years) in the United States
Khera R, Jain S, Pandey A, Agusala V, Kumbhani DJ, Das SR, Berry JD, de Lemos JA, Girotra S. Comparison of Readmission Rates After Acute Myocardial Infarction in 3 Patient Age Groups (18 to 44, 45 to 64, and ≥65 Years) in the United States. The American Journal Of Cardiology 2017, 120: 1761-1767. PMID: 28865892, PMCID: PMC5825232, DOI: 10.1016/j.amjcard.2017.07.081.Peer-Reviewed Original ResearchConceptsYounger age groupsLow-income patientsReadmission ratesAge groupsHigh hospitalization burdenIndex AMI hospitalizationNationwide Readmissions DatabaseRisk of readmissionPatient age groupsAcute myocardial infarctionVulnerable patient groupSignificant resource utilizationMultivariable hierarchical modelsYears of ageHealth care resourcesHealth care systemReadmission periodHospitalization burdenPayer databaseAMI survivorsPost-AMIPatient groupInpatient hospitalizationMyocardial infarctionReadmission