Reni Butler, MD
Professor of Radiology & Biomedical ImagingCards
About
Research
Publications
2026
USPSTF Recommendations and Sociodemographic Factors Impact Mammography Use.
Butler R. USPSTF Recommendations and Sociodemographic Factors Impact Mammography Use. American Journal Of Roentgenology 2026 PMID: 42308096, DOI: 10.2214/ajr.26.35395.Peer-Reviewed Original ResearchUsing artificial intelligence (AI) as a decision support tool in clinic.
Jahanzeb M, Haines K, Shonkwiler E, Kiyani M, Beg S, Benson A, Butler R, Curran W, Drakaki A, Gradishar W, King T, Lieu C, Liu S, Mahtani R, Nabhan C, Nooka A, Rini B, Rugo H, Shah C, Thirman M. Using artificial intelligence (AI) as a decision support tool in clinic. Journal Of Clinical Oncology 2026, 44: e13647-e13647. DOI: 10.1200/jco.2026.44.16_suppl.e13647.Peer-Reviewed Original ResearchMultidisciplinary review panelCancer casesClinical decision support toolMultidisciplinary reviewMaximum achievable scoreClinically meaningful changeDecision support toolComplex cancer casesGenitourinary (GU) cancersMultidisciplinary careGastrointestinal (GI)Competence scoresCancer typesMeaningful changeSupport toolHuman expert reviewExpert recommendationsPanel recommendationsExpert reviewAI modelsAggregate scoreArtificial intelligenceCancer DatabaseDiscordant casesScores
2025
Echogenic Rind Improves Prediction of Malignancy and Tumor Size.
Butler R. Echogenic Rind Improves Prediction of Malignancy and Tumor Size. American Journal Of Roentgenology 2025, 225: e2533927. PMID: 40990585, DOI: 10.2214/ajr.25.33927.Commentaries, Editorials and Letters
2024
Architectural Distortions
Butler R, Durand M, Lanjevar S, Podany P, Andrejeva L, Harigopal M. Architectural Distortions. 2024, 185-207. DOI: 10.1007/978-3-031-65711-5_7.ChaptersInvasive lobular carcinomaLikelihood of malignancyRadial sclerosing lesionsLobular carcinomaSclerosing lesionsTubular carcinomaArchitectural distortionBenign entityDegree of proliferative changeRadial scar/complex sclerosing lesionDuctal carcinoma in situCarcinoma in situInvasive ductal carcinomaChance of malignancyIncidental microscopic findingAbsence of enhancementPost-contrast imagesMyoepithelial cell layerEntrapped glandsField digital mammographyDiscohesive cellsSonographic correlateDuctal carcinomaInvasive carcinomaPalpable massMultimodality Imaging of Postmastectomy Breast Reconstruction Techniques, Complications, and Tumor Recurrence.
Thai J, Sodagari F, Colwell A, Winograd J, Revzin M, Mahmoud H, Mozayan S, Chou S, Destounis S, Butler R. Multimodality Imaging of Postmastectomy Breast Reconstruction Techniques, Complications, and Tumor Recurrence. RadioGraphics 2024, 44: e230070. PMID: 38573814, DOI: 10.1148/rg.230070.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsTumor recurrencePostoperative evaluation of patientsFlap reconstruction methodsImplant-based reconstructionMultimodal imagingBreast reconstruction techniquesFat graft placementBreast cancer recurrenceTissue flap reconstructionEvaluation of patientsNipple-sparing techniquesTissue donor sitesFlap-based reconstructionNipple-areolar complex reconstructionDiagnostic breast imagingUnique patient populationAutologous tissue flapsAbnormal imaging appearancesBreast cancer screeningMastectomy optionLocal recurrenceOncoplastic surgeryDisease recurrenceFlap reconstructionReconstructed breast
2023
Editorial Comment: Artificial Intelligence May Help Define Screening Strategies in Patients With Dense Breasts.
Butler R. Editorial Comment: Artificial Intelligence May Help Define Screening Strategies in Patients With Dense Breasts. American Journal Of Roentgenology 2023, 222: e2330042. PMID: 37556603, DOI: 10.2214/ajr.23.30042.Commentaries, Editorials and LettersPACS-integrated machine learning breast density classifier: clinical validation
Lewin J, Schoenherr S, Seebass M, Lin M, Philpotts L, Etesami M, Butler R, Durand M, Heller S, Heacock L, Moy L, Tocino I, Westerhoff M. PACS-integrated machine learning breast density classifier: clinical validation. Clinical Imaging 2023, 101: 200-205. PMID: 37421715, DOI: 10.1016/j.clinimag.2023.06.023.Peer-Reviewed Original ResearchModern Challenges in Assessing Breast Cancer Screening Strategies: A Call for Added Resources.
Hooley R, Butler R. Modern Challenges in Assessing Breast Cancer Screening Strategies: A Call for Added Resources. Radiology 2023, 306: e230145. PMID: 36749216, DOI: 10.1148/radiol.230145.Commentaries, Editorials and Letters
2022
Optoacoustic Imaging With Decision Support for Differentiation of Benign and Malignant Breast Masses: A 15-Reader Retrospective Study.
Seiler S, Neuschler E, Butler R, Lavin P, Dogan B. Optoacoustic Imaging With Decision Support for Differentiation of Benign and Malignant Breast Masses: A 15-Reader Retrospective Study. American Journal Of Roentgenology 2022, 220: 646-658. PMID: 36475811, DOI: 10.2214/ajr.22.28470.Peer-Reviewed Original ResearchRaising the level of cancer care: Feasibility and reported benefit of a virtual tumor board.
Chiec L, Dempsey N, Agarwal M, Ogden J, Broughman J, Mayo Z, Shonkwiler E, Chaby M, Socinski M, Pegram M, Bilen M, Lieu C, Butler R, Thirman M, Gradishar W, Nooka A, Levy B, Drakaki A, Slovin S, Jahanzeb M. Raising the level of cancer care: Feasibility and reported benefit of a virtual tumor board. Journal Of Clinical Oncology 2022, 40: e18595-e18595. DOI: 10.1200/jco.2022.40.16_suppl.e18595.Peer-Reviewed Original ResearchVirtual tumor boardsHealthcare disparitiesTumor boardLevel of cancer careResponse rateMultidisciplinary tumor boardCancer careOncology careUnmet needsProportion of usersWritten recommendationsDe-identifiedDegree of satisfactionPost-viewingUS facultySurgical oncologistsCareSurgical oncologyPatient managementPatient populationHealthcarePatientsAcademic settingsEducational valueDisparities
Academic Achievements & Community Involvement
Clinical Care
Overview
Reni S. Butler, MD, is a radiologist in the Department of Radiology & Biomedical Imaging who works with patients at the Breast Center. “The patients are my favorite part of my job,” she says. She specializes in breast imaging, reading 3D mammograms, breast ultrasounds and breast MRIs. Dr. Butler also performs core needle biopsies, a procedure that determines if a tumor is benign or cancerous.
“I am thankful to have the opportunity to meet and provide care for women from so many diverse backgrounds,” says Dr. Butler, who is also an associate professor in the Department of Radiology & Biomedical Imaging at Yale School of Medicine. Dr. Butler is a national co-Principal Investigator for a multi-institutional trial of a new technology, opto-acoustic breast imaging. This novel experimental modality aims to improve the accuracy of evaluating breast masses, potentially reducing unnecessary biopsies and detecting additional cancers.
Dr. Butler states, “I am grateful to have the opportunity to make a real difference in someone’s life by detecting an early breast cancer that can be successfully treated. It is so rewarding to know that the state-of-the-art technology and expertise of our doctors at the Smilow Breast Cancer Center can save lives.”
Clinical Specialties
Fact Sheets
Digital Breast Tomosynthesis (3D Mammography)
Learn More on Yale MedicineCancer Screening
Learn More on Yale MedicineBreast Cancer
Learn More on Yale MedicineDense Breasts
Learn More on Yale Medicine
Board Certifications
Diagnostic Radiology
- Certification Organization
- AB of Radiology
- Original Certification Date
- 1997
Yale Medicine News
News
News
- June 17, 2026
Diagnostic Radiology Graduates 16 Residents
- May 04, 2026
Reni Butler, MD, Named Fellow of the American College of Radiology
- July 30, 2024Source: NBC CT
Many women don't understand connection between dense breast tissue and cancer risk
- January 29, 2024
Comprehensive Breast Cancer Care at Smilow Cancer Hospital in New Haven
Get In Touch
Contacts
Radiology & Biomedical Imaging
PO Box 208042
New Haven, CT 06520-8042
United States
Locations
Patient Care Locations
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