2003
Characterization of the CYP4A11 gene, a second CYP4A gene in humans
Bellamine A, Wang Y, Waterman MR, Gainer JV, Dawson EP, Brown NJ, Capdevila JH. Characterization of the CYP4A11 gene, a second CYP4A gene in humans. Archives Of Biochemistry And Biophysics 2003, 409: 221-227. PMID: 12464262, DOI: 10.1016/s0003-9861(02)00545-3.Peer-Reviewed Original ResearchMeSH KeywordsBase SequenceBlotting, SouthernCloning, MolecularCytochrome P-450 CYP4ACytochrome P-450 Enzyme SystemExonsGene DeletionHumansHydroxyeicosatetraenoic AcidsIntronsKidneyMixed Function OxygenasesModels, GeneticMolecular Sequence DataPolymerase Chain ReactionProtein IsoformsReverse Transcriptase Polymerase Chain ReactionRNA
1996
Angiotensin converting enzyme gene polymorphism: Potential silencer motif and impact on progression in IgA nephropathy
Hunley T, Julian B, Phillips J, Summar M, Yoshida H, Horn R, Brown N, Fogo A, Ichikawa I, Kon V. Angiotensin converting enzyme gene polymorphism: Potential silencer motif and impact on progression in IgA nephropathy. Kidney International 1996, 49: 571-577. PMID: 8821846, DOI: 10.1038/ki.1996.81.Peer-Reviewed Original ResearchConceptsRenin-angiotensin systemIgA nephropathyRenal functionDD genotypeMyocardial infarctionCardiovascular diseaseACE genotype frequenciesGene polymorphismsBiopsy-proven IgA nephropathyACE I/D polymorphismAGT 235TEnzyme deletion polymorphismNormal serum creatinineRenal disease progressionACE DD genotypeEnzyme gene polymorphismGenotype frequenciesI gene polymorphismStable creatinineAngiotensin systemSerum creatinineRenal statusVentricular hypertrophyCaucasian patientsRisk factors