2007
A population-based study in Ghana to investigate inter-individual variation in plasma t-PA and PAI-1.
Williams SM, Stocki S, Jiang L, Brew K, Gordon S, Vaughan DE, Brown NJ, Poku KA, Moore JH. A population-based study in Ghana to investigate inter-individual variation in plasma t-PA and PAI-1. Ethnicity & Disease 2007, 17: 492-7. PMID: 17985503.Peer-Reviewed Original ResearchConceptsPlasminogen activator inhibitor-1Tissue-type plasminogen activatorInter-individual variationGenetic architectureSignificant genetic componentGenetic analysisGenetic componentPhenotype informationPopulation-based studyPlasma t-PAActivator inhibitor-1Inhibitor-1Unrelated subjectsLarge-scale population-based studyStudy designChronic disease statusSystolic blood pressurePlasminogen activatorRisk of thrombosisProtein
2005
Proteomic Patterns and Prediction of Glomerulosclerosis and Its Mechanisms
Xu BJ, Shyr Y, Liang X, Ma LJ, Donnert EM, Roberts JD, Zhang X, Kon V, Brown NJ, Caprioli RM, Fogo AB. Proteomic Patterns and Prediction of Glomerulosclerosis and Its Mechanisms. Journal Of The American Society Of Nephrology 2005, 16: 2967-2975. PMID: 16079267, DOI: 10.1681/asn.2005030262.Peer-Reviewed Original ResearchConceptsThymosin beta4Proteomic patternsProtein expression profilesSuch early eventsPlasminogen activator inhibitor-1 expressionMatrix-assisted laser desorption/ionization timeLaser desorption/ionization timeDesorption/ionization timeLaser capture microdissectionEndothelial cellsExpression profilesProtein profilesCapture microdissectionBeta4Cultured glomerular endothelial cellsPlasminogen activator inhibitor-1Early eventsFlight mass spectrometryIonization timeActivator inhibitor-1Inhibitor-1ProteinEarly activationMass spectrometryCells