2016
Efficacy and Safety of Proton-Pump Inhibitors in High-Risk Cardiovascular Subsets of the COGENT Trial
Vaduganathan M, Cannon CP, Cryer BL, Liu Y, Hsieh WH, Doros G, Cohen M, Lanas A, Schnitzer TJ, Shook TL, Lapuerta P, Goldsmith MA, Laine L, Bhatt DL, Investigators C. Efficacy and Safety of Proton-Pump Inhibitors in High-Risk Cardiovascular Subsets of the COGENT Trial. The American Journal Of Medicine 2016, 129: 1002-1005. PMID: 27143321, DOI: 10.1016/j.amjmed.2016.03.042.Peer-Reviewed Original ResearchConceptsDual antiplatelet therapyProton pump inhibitorsAcute coronary syndromePercutaneous coronary interventionCardiovascular eventsCoronary syndromeCoronary interventionGastrointestinal eventsPercutaneous coronary intervention-treated patientsSafety of PPIsUnadjusted Cox proportional hazards modelCox proportional hazards modelDays of randomizationMajor cardiovascular eventsComposite cardiovascular eventsSubset of patientsSafety of omeprazoleProportional hazards modelGastroprotective strategiesMedian followPPI therapyAntiplatelet therapyFrequent indicationHazards modelPatients
1997
Systemic chemotherapy for gastric carcinoma followed by postoperative intraperitoneal therapy
Crookes P, Leichman C, Leichman L, Tan M, Laine L, Stain S, Baranda J, Casagrande Y, Groshen S, Silberman H. Systemic chemotherapy for gastric carcinoma followed by postoperative intraperitoneal therapy. Cancer 1997, 79: 1767-1775. PMID: 9128994, DOI: 10.1002/(sici)1097-0142(19970501)79:9<1767::aid-cncr19>3.0.co;2-w.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAdultAgedAntineoplastic Combined Chemotherapy ProtocolsChemotherapy, AdjuvantCisplatinDrug Administration ScheduleFemaleFloxuridineFluorouracilHumansInfusions, IntravenousInfusions, ParenteralLeucovorinMaleMiddle AgedNeoplasm Recurrence, LocalNeoplasm StagingStomach NeoplasmsTomography, X-Ray ComputedConceptsGastric carcinomaCurative surgerySystemic chemotherapyPostoperative treatmentStage IV gastric carcinomaRate of resectabilitySystemic preoperative chemotherapyGastric cancer resectionPatient underwent surgeryGrade 4 granulocytopeniaPrimary gastric adenocarcinomaMedian followOperative deathsWeekly leucovorinIP chemotherapyPalliative surgeryUnderwent surgeryFirst recurrenceIntraperitoneal chemotherapyIP therapyMedian survivalPreoperative chemotherapyProgressive diseaseRecurrent carcinomaCancer resection