2024
AGA Clinical Practice Update on High-Quality Upper Endoscopy: Expert Review
Nagula S, Parasa S, Laine L, Shah S. AGA Clinical Practice Update on High-Quality Upper Endoscopy: Expert Review. Clinical Gastroenterology And Hepatology 2024, 22: 933-943. PMID: 38385942, DOI: 10.1016/j.cgh.2023.10.034.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsClinical Practice UpdateAmerican Gastroenterological Association (AGA) Institute Clinical Practice UpdateUpper endoscopySurveillance intervalsPractice updateExpert reviewAGA Governing BoardConsensus-based expert opinionStandard biopsy protocolUpper endoscopic examinationPractice advice statementsPeer reviewUpper gastrointestinal mucosaInternational peer reviewAGA membershipBiopsy protocolSurveillance endoscopyDiagnostic yieldHistopathological resultsEndoscopic findingsRetroflexed viewCharacterization of abnormalitiesEndoscopic examinationEndoscopyAdequate visualization
2022
Disparities in Access to Endoscopy for Patients With Upper Gastrointestinal Bleeding Presenting to Emergency Departments
Rodriguez NJ, Zheng N, Mezzacappa C, Canavan M, Laine L, Shung D. Disparities in Access to Endoscopy for Patients With Upper Gastrointestinal Bleeding Presenting to Emergency Departments. Gastroenterology 2022, 164: 1044-1046.e4. PMID: 36228735, PMCID: PMC10083188, DOI: 10.1053/j.gastro.2022.10.001.Peer-Reviewed Original Research
2020
Timing of Endoscopy in Patients Hospitalized with Upper Gastrointestinal Bleeding
Laine L. Timing of Endoscopy in Patients Hospitalized with Upper Gastrointestinal Bleeding. New England Journal Of Medicine 2020, 382: 1361-1363. PMID: 32242363, DOI: 10.1056/nejme2002121.Commentaries, Editorials and Letters
2018
Image-enhanced endoscopy is specific for the diagnosis of non-erosive gastroesophageal reflux disease
Parikh ND, Viana AV, Shah S, Laine L. Image-enhanced endoscopy is specific for the diagnosis of non-erosive gastroesophageal reflux disease. Scandinavian Journal Of Gastroenterology 2018, 53: 260-264. PMID: 29368532, PMCID: PMC6080852, DOI: 10.1080/00365521.2018.1430847.Peer-Reviewed Original ResearchConceptsNon-erosive gastroesophageal reflux diseaseGastroesophageal reflux diseaseImage-enhanced endoscopyNarrow-band imagingReflux diseaseEndoscopic findingsSquamocolumnar junctionUpper endoscopyPatient acceptanceEndoscopyBand imagingI-scanVascularityAdditional studiesPit patternHeartburnPatientsDiseaseDiagnosisImpedance monitoringRRSpecificityFindingsControlCases
2016
Randomized trial of 1‐week versus 2‐week intervals for endoscopic ligation in the treatment of patients with esophageal variceal bleeding
Sheibani S, Khemichian S, Kim JJ, Hou L, Yan AW, Buxbaum J, Dara L, Laine L. Randomized trial of 1‐week versus 2‐week intervals for endoscopic ligation in the treatment of patients with esophageal variceal bleeding. Hepatology 2016, 64: 549-555. PMID: 27082942, PMCID: PMC4956532, DOI: 10.1002/hep.28597.Peer-Reviewed Original ResearchConceptsEsophageal variceal bleedingVariceal bleedingVariceal eradicationAcute esophageal variceal bleedingBeta-blocker therapyProportion of patientsTreatment of patientsNumber of endoscopiesMean numberLigation sessionsChest painPrimary endpointAdverse eventsClinical outcomesEndoscopic ligationLast endoscopyPhysician preferencePatientsBleedingSuccessful ligationEndoscopyConfidence intervalsEradicationLigationWeeks
2014
Low Adherence to Helicobacter pylori Testing in Hospitalized Patients with Bleeding Peptic Ulcer Disease
Kim JJ, Lee JS, Olafsson S, Laine L. Low Adherence to Helicobacter pylori Testing in Hospitalized Patients with Bleeding Peptic Ulcer Disease. Helicobacter 2014, 19: 98-104. PMID: 24617668, DOI: 10.1111/hel.12114.Peer-Reviewed Original ResearchConceptsH. pylori testingProportion of patientsIndex hospitalizationHospitalized patientsConsecutive hospitalized patientsPeptic ulcer diseaseHelicobacter pylori testingInitial endoscopyUlcer diseaseSerologic testingSingle centerEndoscopy databaseSociety guidelinesGastric ulcerLow adherencePatientsUlcersMultivariate analysisHelicobacter pyloriHospitalizationDirect testingBiopsyTestingEndoscopyPyloriCauses of Bleeding and Outcomes in Patients Hospitalized With Upper Gastrointestinal Bleeding
Kim JJ, Sheibani S, Park S, Buxbaum J, Laine L. Causes of Bleeding and Outcomes in Patients Hospitalized With Upper Gastrointestinal Bleeding. Journal Of Clinical Gastroenterology 2014, 48: 113-118. PMID: 23685847, DOI: 10.1097/mcg.0b013e318297fb40.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overEndoscopy, GastrointestinalEsophageal and Gastric VaricesEsophagitisFemaleGastrointestinal HemorrhageHematemesisHospital MortalityHospitalizationHumansLength of StayMaleMedicaidMedicareMelenaMiddle AgedPeptic UlcerPeptic Ulcer HemorrhageRetreatmentRetrospective StudiesUnited StatesConceptsUpper gastrointestinal bleedingGastrointestinal bleedingCommon causeOutcomes of UGIBVariceal upper gastrointestinal bleedingNonvariceal upper gastrointestinal bleedingCause of bleedingRisk of deathLower socioeconomic patientsUrban US hospitalsErosive esophagitisInpatient mortalityRepeat endoscopyUpper endoscopyConsecutive patientsClinical outcomesPeptic ulcerMean ageMedical CenterUrban hospitalPatientsUS hospitalsMultivariate analysisHematemesisEndoscopy
2010
Does Capsule Endoscopy Improve Outcomes in Obscure Gastrointestinal Bleeding? Randomized Trial Versus Dedicated Small Bowel Radiography
Laine L, Sahota A, Shah A. Does Capsule Endoscopy Improve Outcomes in Obscure Gastrointestinal Bleeding? Randomized Trial Versus Dedicated Small Bowel Radiography. Gastroenterology 2010, 138: 1673-1680.e1. PMID: 20138043, DOI: 10.1053/j.gastro.2010.01.047.Peer-Reviewed Original ResearchConceptsObscure GI bleedingObscure gastrointestinal bleedingDiagnostic yieldGI bleedingGastrointestinal bleedingTherapeutic interventionsCapsule endoscopyNegative upper endoscopySubsequent blood transfusionSmall bowel radiographyOccult bleedingPrimary endpointSubsequent hospitalizationMost patientsUpper endoscopyBlood transfusionHemoglobin levelsRandomized trialsVs 5Improved outcomesBleedingContrast radiographyPatientsEndoscopyAbstractText
2009
Does Capsule Endoscopy Improve Outcomes in Obscure GI Bleeding: Randomized Controlled Trial of Capsule Endoscopy vs. Dedicated Small Bowel Radiography
Laine L, Sahota A, Shah A. Does Capsule Endoscopy Improve Outcomes in Obscure GI Bleeding: Randomized Controlled Trial of Capsule Endoscopy vs. Dedicated Small Bowel Radiography. Gastrointestinal Endoscopy 2009, 69: ab99. DOI: 10.1016/j.gie.2009.03.042.Peer-Reviewed Original Research
2008
Esophageal capsule endoscopy for screening and surveillance of esophageal varices in patients with portal hypertension
de Franchis R, Eisen GM, Laine L, Fernandez‐Urien I, Herrerias JM, Brown RD, Fisher L, Vargas HE, Vargo J, Thompson J, Eliakim R. Esophageal capsule endoscopy for screening and surveillance of esophageal varices in patients with portal hypertension. Hepatology 2008, 47: 1595-1603. PMID: 18435461, DOI: 10.1002/hep.22227.Peer-Reviewed Original ResearchConceptsEsophageal varicesEsophageal capsule endoscopyNegative predictive valuePositive predictive valuePredictive valueCapsule endoscopyPortal hypertensionLarge esophageal varicesVariceal gradeLarge varicesMulticenter trialCurrent guidelinesEsophagogastroduodenoscopyTreatment decisionsVaricesCapsule studyPatientsEndoscopyPilot studyDiagnostic performanceEquivalence studyKappa scoresMinimal invasivenessCirrhosisHypertension
2006
Session 5: Treatment of the Acute Bleeding Episode
Laine L, Planas R, Nevens F, Bañares R, Patch D, Bosch J. Session 5: Treatment of the Acute Bleeding Episode. 2006, 217-242. DOI: 10.1002/9780470988831.ch9.Chapters
2000
Comparison of the effect of rofecoxib (a cyclooxygenase 2 inhibitor), ibuprofen, and placebo on the gastroduodenal mucosa of patients with osteoarthritis: A randomized, double‐blind, placebo‐controlled trial
Hawkey C, Laine L, Simon T, Beaulieu A, Maldonado‐Cocco J, Acevedo E, Shahane A, Quan H, Bolognese J, Mortensen E. Comparison of the effect of rofecoxib (a cyclooxygenase 2 inhibitor), ibuprofen, and placebo on the gastroduodenal mucosa of patients with osteoarthritis: A randomized, double‐blind, placebo‐controlled trial. Arthritis & Rheumatism 2000, 43: 370-377. PMID: 10693877, DOI: 10.1002/1529-0131(200002)43:2<370::aid-anr17>3.0.co;2-d.Peer-Reviewed Original ResearchConceptsGastroduodenal ulcersPrespecified criteriaEffect of rofecoxibPlacebo-controlled trialSecondary end pointsDouble-blind studyGastroduodenal ulcerationGastroduodenal mucosaUlcer incidenceCyclooxygenase-2Side effectsUlcersEnd pointEffective doseRofecoxibWeeksPlaceboPatientsOsteoarthritisIncidenceDoseIbuprofenUlcerationMucosaEndoscopy
1998
Effect of blood on rapid urease testing of gastric mucosal biopsy specimens
Laine L, Sidhom O, Emami S, Estrada R, Cohen H. Effect of blood on rapid urease testing of gastric mucosal biopsy specimens. Gastrointestinal Endoscopy 1998, 47: 141-143. PMID: 9512278, DOI: 10.1016/s0016-5107(98)70346-3.Peer-Reviewed Original ResearchConceptsRapid urease testBiopsy specimensUrease testEffect of bloodRapid urease test resultsGastric mucosal biopsy specimensMucosal biopsy specimensRapid urease testingGastric biopsy specimensUrease test resultsGastric bodyUrease testingPositive testDiscordant resultsBloodCLOtestPyloriTekHoursPatientsAntrumBiopsyMucosaEndoscopy
1994
Lack of uniformity in evaluation of endoscopic prognostic features of bleeding ulcers
Laine L, Freeman M, Cohen H. Lack of uniformity in evaluation of endoscopic prognostic features of bleeding ulcers. Gastrointestinal Endoscopy 1994, 40: 411-417. PMID: 7926529, DOI: 10.1016/s0016-5107(94)70202-0.Peer-Reviewed Original ResearchConceptsLevel of agreementUpper gastrointestinal endoscopyType of procedureBrief teaching sessionUlcer stigmataEndoscopic featuresPrognostic featuresRecent hemorrhageUlcer appearanceGastrointestinal endoscopyAmerican CollegeEndoscopic experienceAdditional slidesUlcersTeaching sessionsEndoscopistsYears of experienceShort teaching sessionEndoscopyCorrect answersMonthsLack of uniformitySessionsStigmaTotal number
1992
Indications, Technique, and Complications of Balloon Tamponade for Variceal Gastrointestinal Bleeding
Cook D, Laine L. Indications, Technique, and Complications of Balloon Tamponade for Variceal Gastrointestinal Bleeding. Journal Of Intensive Care Medicine 1992, 7: 212-218. PMID: 10147943, DOI: 10.1177/088506669200700408.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsBalloon tamponadeAcute upper gastrointestinal haemorrhageVariceal gastrointestinal bleedingUpper gastrointestinal hemorrhageBalloon insertionGastrointestinal bleedingGastrointestinal hemorrhageEsophageal varicesPotential complicationsTherapeutic endoscopyTimely treatmentTamponadeComplicationsVaricesBleedingSclerotherapyHemorrhagePatientsEndoscopyHemostatis