2016
Randomized trial of 1‐week versus 2‐week intervals for endoscopic ligation in the treatment of patients with esophageal variceal bleeding
Sheibani S, Khemichian S, Kim JJ, Hou L, Yan AW, Buxbaum J, Dara L, Laine L. Randomized trial of 1‐week versus 2‐week intervals for endoscopic ligation in the treatment of patients with esophageal variceal bleeding. Hepatology 2016, 64: 549-555. PMID: 27082942, PMCID: PMC4956532, DOI: 10.1002/hep.28597.Peer-Reviewed Original ResearchConceptsEsophageal variceal bleedingVariceal bleedingVariceal eradicationAcute esophageal variceal bleedingBeta-blocker therapyProportion of patientsTreatment of patientsNumber of endoscopiesMean numberLigation sessionsChest painPrimary endpointAdverse eventsClinical outcomesEndoscopic ligationLast endoscopyPhysician preferencePatientsBleedingSuccessful ligationEndoscopyConfidence intervalsEradicationLigationWeeks
1995
Endoscopic ligation compared with sclerotherapy for treatment of esophageal variceal bleeding. A meta-analysis.
Laine L, Cook D. Endoscopic ligation compared with sclerotherapy for treatment of esophageal variceal bleeding. A meta-analysis. Annals Of Internal Medicine 1995, 123: 280-7. PMID: 7611595, DOI: 10.7326/0003-4819-123-4-199508150-00007.Peer-Reviewed Original ResearchConceptsEsophageal variceal bleedingTreatment of patientsEndoscopic ligationVariceal bleedingEsophageal varicesEndoscopic treatmentDuplicate data abstractionDuplicate independent reviewEndoscopic treatment sessionsRate of deathRelevant primary articlesReview of citationsVariceal obliterationBacterial peritonitisLigation therapyPulmonary infectionEsophageal strictureMethodologic qualitySclerotherapyMortality rateTreatment sessionsPatientsRelevant articlesPrimary investigatorUnpublished studies
1993
Endoscopic ligation compared with sclerotherapy for the treatment of bleeding esophageal varices.
Laine L, el-Newihi HM, Migikovsky B, Sloane R, Garcia F. Endoscopic ligation compared with sclerotherapy for the treatment of bleeding esophageal varices. Annals Of Internal Medicine 1993, 119: 1-7. PMID: 8498757, DOI: 10.7326/0003-4819-119-1-199307010-00001.Peer-Reviewed Original ResearchConceptsRisk of deathEsophageal varicesVariceal eradicationEndoscopic examinationLigation groupInitial endoscopic examinationUrban county hospitalKaplan-Meier estimatesLigation treatmentTransfusion requirementsVariceal obliterationFurther bleedingHospital stayEndoscopic sclerotherapyEndoscopic therapyEsophageal ulcerLocal complicationsRecurrent varicesBlood transfusionSevere bleedingEndoscopic ligationTreatment failureEsophageal strictureCounty HospitalSclerotherapy