2008
Foreign-body ingestion: characteristics and outcomes in a lower socioeconomic population with predominantly intentional ingestion
Palta R, Sahota A, Bemarki A, Salama P, Simpson N, Laine L. Foreign-body ingestion: characteristics and outcomes in a lower socioeconomic population with predominantly intentional ingestion. Gastrointestinal Endoscopy 2008, 69: 426-433. PMID: 19019363, DOI: 10.1016/j.gie.2008.05.072.Peer-Reviewed Original ResearchConceptsForeign body ingestionUrban county hospitalIntentional ingestionEndoscopic extractionCounty HospitalPsychiatric patientsLow socioeconomic status populationRetrospective case seriesLow socioeconomic populationOverall success rateCase seriesRetrospective reviewEndoscopic managementIngestion casesMedical recordsPrior ingestionAccidental ingestionPatientsSocioeconomic populationsSurgeryStatus populationIngestionPerforationSuccess rateHospital
2005
The effect of GI bleeding on Helicobacter pylori diagnostic testing: a prospective study at the time of bleeding and 1 month later
Laine LA, Nathwani RA, Naritoku W. The effect of GI bleeding on Helicobacter pylori diagnostic testing: a prospective study at the time of bleeding and 1 month later. Gastrointestinal Endoscopy 2005, 62: 853-859. PMID: 16301025, DOI: 10.1016/j.gie.2005.09.019.Peer-Reviewed Original ResearchConceptsH pylori densityAcute GI bleedingInflammatory cell infiltrationH pyloriGI bleedingHistologic examinationCohort studyCell infiltrationDiagnostic testingBlinded histologic examinationH pylori testingAcute variceal bleedingProspective cohort studyUrban county hospitalProton pump inhibitorsTime of bleedingRapid urease testingVariceal bleedingCase seriesEndoscopic biopsyProspective studyPump inhibitorsBiopsy specimensUrease testingCounty Hospital
1993
Endoscopic ligation compared with sclerotherapy for the treatment of bleeding esophageal varices.
Laine L, el-Newihi HM, Migikovsky B, Sloane R, Garcia F. Endoscopic ligation compared with sclerotherapy for the treatment of bleeding esophageal varices. Annals Of Internal Medicine 1993, 119: 1-7. PMID: 8498757, DOI: 10.7326/0003-4819-119-1-199307010-00001.Peer-Reviewed Original ResearchConceptsRisk of deathEsophageal varicesVariceal eradicationEndoscopic examinationLigation groupInitial endoscopic examinationUrban county hospitalKaplan-Meier estimatesLigation treatmentTransfusion requirementsVariceal obliterationFurther bleedingHospital stayEndoscopic sclerotherapyEndoscopic therapyEsophageal ulcerLocal complicationsRecurrent varicesBlood transfusionSevere bleedingEndoscopic ligationTreatment failureEsophageal strictureCounty HospitalSclerotherapyProtein-losing enteropathy and hypoalbuminemia in AIDS
Laine L, Garcia F, McGilligan K, Malinko A, Sinatra F, Thomas D. Protein-losing enteropathy and hypoalbuminemia in AIDS. AIDS 1993, 7: 837-840. PMID: 8363760, DOI: 10.1097/00002030-199306000-00012.Peer-Reviewed Original ResearchConceptsNormal bowel habitsProtein-losing enteropathyFecal alphaBowel habitsNormal serum albuminNormal albuminFecal alpha 1Normal albumin groupUrban county hospitalGroup of patientsDevelopment of hypoalbuminemiaUpper endoscopyFlexible sigmoidoscopyAlbumin groupMucosal diseaseCounty HospitalHypoalbuminemiaMAIN OUTCOMEProspective assessmentSerum albuminPatientsLinear regression analysisDiarrheaSignificant negative correlationGross abnormalities
1989
Multipolar electrocoagulation in the treatment of peptic ulcers with nonbleeding visible vessels. A prospective, controlled trial.
Laine L. Multipolar electrocoagulation in the treatment of peptic ulcers with nonbleeding visible vessels. A prospective, controlled trial. Annals Of Internal Medicine 1989, 110: 510-4. PMID: 2647014, DOI: 10.7326/0003-4819-110-7-510.Peer-Reviewed Original ResearchConceptsNonbleeding visible vesselMultipolar electrocoagulationVisible vesselControl groupMajor upper gastrointestinal hemorrhageMean transfusion requirementSham-controlled trialUpper gastrointestinal hemorrhageUnstable vital signsSafety of treatmentCost of hospitalizationUnits of bloodEndoscopic evidenceGastrointestinal hemorrhageTransfusion requirementsUrgent surgeryEmergency surgeryHospital daysEndoscopic treatmentOverall mortalityPeptic ulcerCounty HospitalAspirate samplesDiagnostic endoscopyTreatment groups