Pharmacogenomics and Clinical Biomarkers in Drug Discovery and Development
Ross JS, Symmans WF, Pusztai L, Hortobagyi GN. Pharmacogenomics and Clinical Biomarkers in Drug Discovery and Development. American Journal Of Clinical Pathology 2005, 124: s29-s41. PMID: 16468416, DOI: 10.1309/xyqafanapync6x59.Peer-Reviewed Original ResearchConceptsHuman genome sequenceGene expression profilesGenome sequenceEpigenetic eventsExpression profilesProteomics researchDrug discoveryRapid evolutionComputational biologyPharmaceutical industryMolecular diagnosticsDiscoveryFurther understandingBiosensorRNABiologyAnticancerSequenceClinical biomarkersAnti-inflammatory drugsDrug efficacyToxicityPrediction of responseDevelopmentContinuous technological advancements