2024
Twenty Years of Sustained Improvement in Quality of Care and Outcomes for Patients Hospitalized With Stroke or Transient Ischemic Attack: Data From The Get With The Guidelines-Stroke Program
Xian Y, Li S, Jiang T, Beon C, Poudel R, Thomas K, Reeves M, Smith E, Saver J, Sheth K, Messé S, Schwamm L, Fonarow G. Twenty Years of Sustained Improvement in Quality of Care and Outcomes for Patients Hospitalized With Stroke or Transient Ischemic Attack: Data From The Get With The Guidelines-Stroke Program. Stroke 2024, 55: 2599-2610. PMID: 39429153, PMCID: PMC11518659, DOI: 10.1161/strokeaha.124.048174.Peer-Reviewed Original ResearchConceptsGuidelines-Stroke programEvidence-based stroke careDoor-to-needle timeTransient ischemic attackGuidelines-Stroke hospitalsEvidence-based careQuality of careSmoking cessation counselingSustained improvementQuality improvement initiativesSkilled nursing facilityIndependence of patientsAcute ischemic strokeIschemic strokeRelevant to patientsIschemic attackDoor-to-puncture timeCessation counselingGuidelines-StrokeAssociated with sustained improvementStroke careDysphagia screeningNursing facilitiesHospital characteristicsImprovement initiativesMapping the Ecological Terrain of Stroke Prehospital Delay: A Nationwide Registry Study
Dhand A, Reeves M, Mu Y, Rosner B, Rothfeld-Wehrwein Z, Nieves A, Dhongade V, Jarman M, Bergmark R, Semco R, Ader J, Marshall B, Goedel W, Fonarow G, Smith E, Saver J, Schwamm L, Sheth K. Mapping the Ecological Terrain of Stroke Prehospital Delay: A Nationwide Registry Study. Stroke 2024, 55: 1507-1516. PMID: 38787926, PMCID: PMC11299104, DOI: 10.1161/strokeaha.123.045521.Peer-Reviewed Original ResearchConceptsSocial Vulnerability IndexPrehospital delayHospital arrivalZIP Code Tabulation AreasEmergency medical servicesCommunity-level social vulnerabilityGuidelines-Stroke registryCommunity socioeconomic statusCommunity-level factorsPatient-level factorsNationwide registry studyAmerican Heart AssociationSocial vulnerabilityCox proportional hazards modelsSocially vulnerable areasAssociated with delaySocial determinantsProportional hazards modelAcute stroke treatmentGeospatial mappingSocioeconomic statusMedical servicesIncreased social vulnerabilityPrimary exposureQuartile 3
2023
Antithrombotic and Statin Prescription After Intracerebral Hemorrhage in the Get With The Guidelines-Stroke Registry
Murthy S, Zhang C, Shah S, Schwamm L, Fonarow G, Smith E, Bhatt D, Ziai W, Kamel H, Sheth K. Antithrombotic and Statin Prescription After Intracerebral Hemorrhage in the Get With The Guidelines-Stroke Registry. Stroke 2023, 54: 2972-2980. PMID: 37942641, PMCID: PMC10842167, DOI: 10.1161/strokeaha.123.043194.Peer-Reviewed Original ResearchConceptsIschemic vascular diseaseProportion of patientsGuidelines-Stroke registryLipid-lowering therapyIntracerebral hemorrhageVascular diseaseStatin therapyAnticoagulation therapyCardiovascular eventsAtrial fibrillationFuture major cardiovascular eventsLower admission National InstitutesPrevious lipid-lowering therapyAdmission National InstitutesFavorable discharge outcomeIschemic cardiovascular eventsHealth Stroke ScaleMajor cardiovascular eventsLipid-lowering medicationsCross-sectional studyMultiple logistic regressionLogistic regression analysisAntiplatelet medicationsAntiplatelet therapyStatin medication
2018
STAIR X
Liebeskind D, Derdeyn C, Wechsler L, Albers G, Ankerud E, Boltze J, Broderick J, Campbell B, Elkind M, En’Wezoh D, Furlan A, Gorelick P, Grotta J, Hess D, Hancock A, Hill M, Holt W, Hutchison R, Kim W, Lansberg M, LaScalza S, Latour L, Liberman M, Luby M, Lyden P, Majidi S, Mansi C, Nogueira R, Saver J, Savitz S, Schwamm L, Selim M, Sheth K, Simpkins A, Singhal A, Solberg Y, Steinberg G, Taylor T, Tymianski M, Yoo A. STAIR X. Stroke 2018, 49: 2241-2247. PMID: 30355006, DOI: 10.1161/strokeaha.118.021424.Peer-Reviewed Original ResearchBiomarkersCerebral AngiographyDevice ApprovalEducationEndovascular ProceduresGuidelines as TopicHumansIntracranial HemorrhagesPrecision MedicineRandomized Controlled Trials as TopicRegistriesResearch DesignStrokeThrombectomyThrombolytic TherapyTreatment OutcomeUnited StatesUnited States Food and Drug Administration
2016
Predicting survival after acute civilian penetrating brain injuries
Muehlschlegel S, Ayturk D, Ahlawat A, Izzy S, Scalea TM, Stein DM, Emhoff T, Sheth KN. Predicting survival after acute civilian penetrating brain injuries. Neurology 2016, 87: 2244-2253. PMID: 27784772, PMCID: PMC5123553, DOI: 10.1212/wnl.0000000000003355.Peer-Reviewed Original ResearchConceptsRadiologic factorsBrain injuryMotor Glasgow Coma ScaleLower Injury Severity ScoreLevel 1 trauma centerLower international normalized ratioUS level 1 trauma centersSurvival prediction scoreInjury Severity ScoreGlasgow Coma ScaleInternational normalized ratioMultivariable logistic regressionTraumatic brain injurySelf-inflicted injurySurvival prediction toolHospital dischargeComa ScaleLocal traumaPenetrating injuryTrauma centerMean ageNormalized ratioFemale sexSeverity scorePupillary reactivity