2024
Impact of acute kidney injury response on survival and liver transplant rates in hospitalized patients with cirrhosis awaiting liver transplantation: Results from the HRS-HARMONY consortium
Li X, Ouyang T, Belcher J, Patidar K, Cullaro G, Asrani S, Wadei H, Simonetto D, Regner K, Dageforde L, Przybyszewski E, Wilechansky R, Sharma P, Ufere N, Duarte-Rojo A, Wahid N, Orman E, St. Hillien S, Robinson J, Chung R, Allegretti A, collaborative I. Impact of acute kidney injury response on survival and liver transplant rates in hospitalized patients with cirrhosis awaiting liver transplantation: Results from the HRS-HARMONY consortium. Liver Transplantation 2024, 30: 1106-1115. PMID: 39073567, DOI: 10.1097/lvt.0000000000000445.Peer-Reviewed Original ResearchAKI responseAcute kidney injuryTransplant-free survivalLiver transplantationLT ratesCirrhosis patientsNon-respondersTime of liver transplantationCourse of hospitalized patientsNo responseRetrospective multicenter studyMELD-Na scoreResponse to therapyResponse to treatmentLiver transplant ratesRate of LTOverall survivalMulticenter studyKidney injuryCirrhosis etiologyCirrhosisHospitalized patientsTransplantationPatientsInjury response
2021
Urinary NGAL as a Diagnostic and Prognostic Marker for Acute Kidney Injury in Cirrhosis: A Prospective Study
Allegretti AS, Parada XV, Endres P, Zhao S, Krinsky S, St. Hillien SA, Kalim S, Nigwekar SU, Flood JG, Nixon A, Simonetto DA, Juncos LA, Karakala N, Wadei HM, Regner KR, Belcher JM, Nadim MK, Garcia-Tsao G, Velez JCQ, Parikh SM, Chung RT. Urinary NGAL as a Diagnostic and Prognostic Marker for Acute Kidney Injury in Cirrhosis: A Prospective Study. Clinical And Translational Gastroenterology 2021, 12: e00359. PMID: 33979307, PMCID: PMC8116001, DOI: 10.14309/ctg.0000000000000359.Peer-Reviewed Original ResearchConceptsNeutrophil gelatinase-associated lipocalinUrinary neutrophil gelatinase-associated lipocalinAcute kidney injuryAcute tubular necrosisPrerenal acute kidney injuryHepatorenal syndromeKidney injuryC-statisticManagement of AKITypes of AKIEnd-stage liver disease (MELD) scoreTransplant-free survivalLiver Disease scoreMedian serum creatinineGelatinase-associated lipocalinPrediction of mortalityNet reclassification indexDiscrimination incrementProspective cohortSerum creatinineTubular necrosisProspective studyReclassification indexUnadjusted analysesPrognostic marker