2014
Urinary Biomarkers and Progression of AKI in Patients with Cirrhosis
Belcher JM, Garcia-Tsao G, Sanyal AJ, Thiessen-Philbrook H, Peixoto AJ, Perazella MA, Ansari N, Lim J, Coca SG, Parikh CR. Urinary Biomarkers and Progression of AKI in Patients with Cirrhosis. Clinical Journal Of The American Society Of Nephrology 2014, 9: 1857-1867. PMID: 25183658, PMCID: PMC4220770, DOI: 10.2215/cjn.09430913.Peer-Reviewed Original ResearchMeSH KeywordsAcute Kidney InjuryAcute-Phase ProteinsAdultAgedAlbuminuriaBiomarkersDisease ProgressionFatty Acid-Binding ProteinsFemaleHepatitis A Virus Cellular Receptor 1Hospital MortalityHumansInterleukin-18Lipocalin-2LipocalinsLiver CirrhosisMaleMembrane GlycoproteinsMiddle AgedPredictive Value of TestsProspective StudiesProto-Oncogene ProteinsReceptors, VirusSodiumConceptsProgression of AKIAKI progressionIL-18Urinary biomarkersHospital mortalityKIM-1End-stage liver disease (MELD) scoreL-FABPStage liver disease scoreNeutrophil gelatinase-associated lipocalinAKI Network criteriaLiver Disease scoreProspective cohort studyGelatinase-associated lipocalinNet reclassification indexUnited States medical centersKey clinical variablesRobust clinical modelKidney injuryCohort studySevere complicationsLiver cirrhosisRisk stratificationClinical variablesMarker levels
2011
Clinical Applications of Biomarkers for Acute Kidney Injury
Belcher JM, Edelstein CL, Parikh CR. Clinical Applications of Biomarkers for Acute Kidney Injury. American Journal Of Kidney Diseases 2011, 57: 930-940. PMID: 21411200, DOI: 10.1053/j.ajkd.2010.11.032.BooksConceptsDiagnosis of AKIAcute kidney injurySerum creatinine levelsKidney injuryCreatinine levelsIL-18Multiple novel biomarkersProspective trial designUtility of biomarkersAdequate poweringSuccessful human trialsInterleukin-18Kidney functionNovel therapiesDifferential diagnosisHuman trialsNovel biomarkersTrial designAnimal studiesTherapeutic efficacyInjuryDiagnosisEarly detectionBiomarkersPotential role