1995
Verapamil treatment attenuates immunoreactive GFAP at cerebral cortical lesion site
Klepper S, Naftolin F, Piepmeier J. Verapamil treatment attenuates immunoreactive GFAP at cerebral cortical lesion site. Brain Research 1995, 695: 245-249. PMID: 8556338, DOI: 10.1016/0006-8993(95)00825-b.Peer-Reviewed Original ResearchConceptsGFAP-like immunoreactivityGlial fibrillary acidic proteinSaline groupCortical lesionsLocal injectionNeedle lesionsLesion siteL-type calcium channel blockerCerebral cortical lesionsCortical lesion sitesL-type calcium channelsCalcium channel blockersSprague-Dawley ratsImmunoreactive glial fibrillary acidic proteinTime of lesioningFibrillary acidic proteinH post lesionTransmembrane calcium fluxVerapamil treatmentReactive astrocytesPost lesionContralateral hemisphereChannel blockersCalcium channelsAntigen labeling
1993
Low-grade astrocytomas may arise from different astrocyte lineages.
Piepmeier J, Fried I, Makuch R. Low-grade astrocytomas may arise from different astrocyte lineages. Neurosurgery 1993, 33: 627-32. PMID: 8232801, DOI: 10.1227/00006123-199310000-00010.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAstrocytesAstrocytomaBiomarkers, TumorCell Transformation, NeoplasticFemaleGangliosidesGlial Fibrillary Acidic ProteinHumansMaleMiddle AgedSupratentorial NeoplasmsConceptsLow-grade astrocytomasGlial fibrillary acidic protein-positive cellsFibrillary acidic proteinProtein-positive cellsAstrocyte lineagePreoperative symptomsAnti-glial fibrillary acidic proteinAcidic proteinGlial fibrillary acidic proteinLong preoperative historyCommon histological featuresDifferent clinical manifestationsPercentage of cellsPreoperative historyClinical manifestationsHistological featuresImaging featuresRate of proliferationImmunohistochemical analysisAstrocytic phenotypeNeoplastic cellsType 2White matterAstrocytomasTumors