2009
Current concepts in the evaluation and management of WHO grade II gliomas
Piepmeier JM. Current concepts in the evaluation and management of WHO grade II gliomas. Journal Of Neuro-Oncology 2009, 92: 253-259. PMID: 19357953, DOI: 10.1007/s11060-009-9870-z.Peer-Reviewed Original ResearchConceptsHigh-grade lesionsGrade II gliomasRandomized clinical trialsLow-grade lesionsAdditional genetic mutationsAdjuvant treatmentAppropriate therapyClinical trialsClinical reportsFatal diseaseLesionsUnique lesionGenetic mutationsCurrent conceptsContinued investigationGliomasRecent findingsSelection criteriaPatientsTherapyTumorsDiseaseTrials
2006
New methods for direct delivery of chemotherapy for treating brain tumors.
Sawyer AJ, Piepmeier JM, Saltzman WM. New methods for direct delivery of chemotherapy for treating brain tumors. The Yale Journal Of Biology And Medicine 2006, 79: 141-52. PMID: 17940624, PMCID: PMC1994797.Peer-Reviewed Original ResearchConceptsConvection-enhanced deliveryBrain tumorsPrimary malignant brain tumorLocal deliveryBlood-brain barrierMalignant brain tumorsStandard chemotherapeutic drugsBrain cancer treatmentAnti-cancer therapyMedian survivalInfusion siteSevere formMalignant cellsNew delivery strategiesChemotherapy drugsChemotherapyDiagnostic imagingTumorsChemotherapeutic drugsCancer treatmentDrugsInvasive cellsSource of drugsDelivery strategiesBrain
2000
A neurosurgeon's perspective on the neuropathology of low-grade gliomas
Piepmeier J. A neurosurgeon's perspective on the neuropathology of low-grade gliomas. Brain Tumor Pathology 2000, 17: 85-88. PMID: 11210176, DOI: 10.1007/bf02482740.Peer-Reviewed Original Research
1985
A phase I trial of naloxone treatment in acute spinal cord injury.
Flamm E, Young W, Collins W, Piepmeier J, Clifton G, Fischer B. A phase I trial of naloxone treatment in acute spinal cord injury. Journal Of Neurosurgery 1985, 63: 390-7. PMID: 3894597, DOI: 10.3171/jns.1985.63.3.0390.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedClinical Trials as TopicEvoked Potentials, SomatosensoryFemaleHumansMaleMiddle AgedNaloxoneSpinal Cord InjuriesConceptsGroup 2 patientsSpinal cord injuryAcute spinal cord injuryPhase I trialTime of admissionLoading doseCord injuryMaintenance doseI trialExperimental spinal cord injuryComplete neurological deficitGroup 1 patientsWeeks of admissionDose-related fashionTreatment of patientsOpiate antagonist naloxoneIncomplete deficitsMaintenance infusionNeurological deficitsNeurological statusNaloxone treatmentNeurological examinationAntagonist naloxoneInitial doseContinuous infusion