2008
Flexibility in the site of exon junction complex deposition revealed by functional group and RNA secondary structure alterations in the splicing substrate
Mishler DM, Christ AB, Steitz JA. Flexibility in the site of exon junction complex deposition revealed by functional group and RNA secondary structure alterations in the splicing substrate. RNA 2008, 14: 2657-2670. PMID: 18952819, PMCID: PMC2590960, DOI: 10.1261/rna.1312808.Peer-Reviewed Original ResearchConceptsExon junction complexRNA secondary structureEJC depositionSplicing substrateMammalian nonsense-mediated mRNA decayNonsense-mediated mRNA decaySecondary structureStretches of DNATranslational regulationMRNA decayCoimmunoprecipitation assaysJunction complexSecondary structure alterationsDNA nucleotidesStructure alterationsH protectionUpstream shiftToeprintingExonsSitesNucleotidesDNACrystal structureDeposition sitesMRNA
1996
A small nucleolar RNA requirement for site-specific ribose methylation of rRNA in Xenopus
Tycowski K, Smith C, Shu M, Steitz J. A small nucleolar RNA requirement for site-specific ribose methylation of rRNA in Xenopus. Proceedings Of The National Academy Of Sciences Of The United States Of America 1996, 93: 14480-14485. PMID: 8962077, PMCID: PMC26158, DOI: 10.1073/pnas.93.25.14480.Peer-Reviewed Original ResearchConceptsSmall nucleolar RNA (snoRNA) speciesSite-specific ribose methylationXenopus oocyte systemSnoRNA speciesSnoRNA genesRibose methylationVertebrate cellsRNA speciesMultiple homologsSnoRNA stabilityRRNASnoRNAsOocyte systemRNA requirementsXenopusXenopus oocytesFibrillarinMethylationSpeciesOocytesVertebratesHomologCloningGenesTranscripts