2023
Putting the brakes on synchrony: VIP interneurons tune visually evoked rhythmic activity
Perrenoud Q, Cardin J. Putting the brakes on synchrony: VIP interneurons tune visually evoked rhythmic activity. Neuron 2023, 111: 297-299. PMID: 36731427, DOI: 10.1016/j.neuron.2023.01.004.Peer-Reviewed Original Research
2010
Cellular Mechanisms of Temporal Sensitivity in Visual Cortex Neurons
Cardin JA, Kumbhani RD, Contreras D, Palmer LA. Cellular Mechanisms of Temporal Sensitivity in Visual Cortex Neurons. Journal Of Neuroscience 2010, 30: 3652-3662. PMID: 20219999, PMCID: PMC2880457, DOI: 10.1523/jneurosci.5279-09.2010.Peer-Reviewed Original ResearchConceptsLayer 4 neuronsCortical neuronsSensory-evoked synaptic inputsVisual cortex neuronsCellular mechanismsPrimary visual cortexCortex neuronsInhibitory interneuronsCortical functionExcitatory neuronsSynaptic inputsMembrane potential responsesSpike precisionVisual cortexCortical layersExcitatory conductanceNeuronsCoincident inputsInput integrationSynchronous inputsCortexNonlinear summationTemporal sensitivityAcuityInterneuronsTargeted optogenetic stimulation and recording of neurons in vivo using cell-type-specific expression of Channelrhodopsin-2
Cardin JA, Carlén M, Meletis K, Knoblich U, Zhang F, Deisseroth K, Tsai LH, Moore CI. Targeted optogenetic stimulation and recording of neurons in vivo using cell-type-specific expression of Channelrhodopsin-2. Nature Protocols 2010, 5: 247-254. PMID: 20134425, PMCID: PMC3655719, DOI: 10.1038/nprot.2009.228.Peer-Reviewed Original ResearchConceptsOptical interferenceMajor long-term goalViral vectorsCell-type selectivityRecording of neuronsOptogenetic stimulationChannelrhodopsin-2Cre-dependent expressionBrain circuit functionSelective cell typesInhibitory interneuronsIntracellular recordingsVivo electrophysiologyExcitatory neuronsIntact brainType selectivityNeural subtypesOptogenetic techniquesSpecific populationsNeural activityCircuit functionNeuronsInterferenceCell typesStimulation
2009
Pinacidil induces vascular dilation and hyperemia in vivo and does not impact biophysical properties of neurons and astrocytes in vitro
Cao R, Higashikubo B, Cardin J, Knoblich U, Ramos R, Nelson M, Moore C, Brumberg J. Pinacidil induces vascular dilation and hyperemia in vivo and does not impact biophysical properties of neurons and astrocytes in vitro. Cleveland Clinic Journal Of Medicine 2009, 76: s80-s85. PMID: 19380306, PMCID: PMC4406396, DOI: 10.3949/ccjm.76.s2.16.Peer-Reviewed Original ResearchConceptsBlood volumeApplication of pinacidilWhole-cell recordingsLocal blood volumeFunctional hyperemiaVascular dilationNeocortical slicesAnesthetized ratsAwake miceSmooth muscleSelective agonistPinacidilImpact of hemodynamicsIntrinsic modulatorHyperemiaNeural activityVasodilationNeuronsVivoBiophysical propertiesNeural systemsHemodynamicsAgonistsNeocortexRats
1998
Lucifer Yellow filling of area X-projecting neurons in the high vocal center of female canaries
Benton S, Cardin J, DeVoogd T. Lucifer Yellow filling of area X-projecting neurons in the high vocal center of female canaries. Brain Research 1998, 799: 138-147. PMID: 9666104, DOI: 10.1016/s0006-8993(98)00485-5.Peer-Reviewed Original ResearchConceptsHigh vocal centerArea XForebrain nucleiCell classesLucifer Yellow fillingAuditory inputAnterior forebrain pathwayFemale canariesSlice preparationMajor projectionsSomatosensory inputHVC neuronsNeuronal populationsShort dendritesSensorimotor integrationForebrain pathwayNeuronsLucifer YellowVocal motorImmunocytochemical reactionSong systemDefinitive evidenceRelevant changesPrevious studiesRelated changes