2019
Outcomes and Anticoagulation Use After Catheter Ablation for Atrial Fibrillation
Freeman JV, Shrader P, Pieper KS, Allen LA, Chan PS, Fonarow GC, Gersh BJ, Kowey PR, Mahaffey KW, Naccarelli G, Reiffel JA, Singer DE, Go AS, Hylek EM, Steinberg BA, Peterson ED, Piccini JP. Outcomes and Anticoagulation Use After Catheter Ablation for Atrial Fibrillation. Circulation Arrhythmia And Electrophysiology 2019, 12: e007612. PMID: 31830822, DOI: 10.1161/circep.119.007612.Peer-Reviewed Original ResearchConceptsAF catheter ablationOral anticoagulationRisk of strokeAF ablationCatheter ablationAntiarrhythmic medicationsDe novo AF ablationDiscontinuation of OACPropensity score-matched cohortAtrial fibrillation catheter ablationAF ablation patientsAnti-arrhythmic medicationsAtrial Fibrillation RegistryStroke prevention therapyBetter Informed TreatmentCohort of patientsPatterns of treatmentProportional hazards regressionUS national registryAnticoagulation useCause deathMajor bleedingSystemic embolismCardiovascular deathCause hospitalizationComparison of Long-Term Adverse Outcomes in Patients With Atrial Fibrillation Having Ablation Versus Antiarrhythmic Medications
Freeman JV, Tabada GH, Reynolds K, Sung SH, Singer DE, Wang PJ, Liu TI, Gupta N, Hlatky MA, Go AS. Comparison of Long-Term Adverse Outcomes in Patients With Atrial Fibrillation Having Ablation Versus Antiarrhythmic Medications. The American Journal Of Cardiology 2019, 125: 553-561. PMID: 31843233, PMCID: PMC6987016, DOI: 10.1016/j.amjcard.2019.11.004.Peer-Reviewed Original ResearchConceptsTransient ischemic attackChronic antiarrhythmic therapyHeart failure hospitalizationIschemic attackAntiarrhythmic therapyAF ablationIschemic strokeIntracranial hemorrhageAntiarrhythmic medicationsFailure hospitalizationCatheter ablationAdverse outcomesAdjusted ratesKaiser Permanente Northern CaliforniaLong-term adverse outcomesAtrial fibrillation catheter ablationAF catheter ablationHigh-dimensional propensity scoreHistory of diabetesHistory of hypertensionCoronary heart diseaseHealthcare delivery systemCause hospitalizationObservational cohortHeart failure
2017
Treatment of Atrial Fibrillation and Concordance With the American Heart Association/American College of Cardiology/Heart Rhythm Society Guidelines
Barnett AS, Kim S, Fonarow GC, Thomas LE, Reiffel JA, Allen LA, Freeman JV, Naccarelli G, Mahaffey KW, Go AS, Kowey PR, Ansell JE, Gersh BJ, Hylek EM, Peterson ED, Piccini JP. Treatment of Atrial Fibrillation and Concordance With the American Heart Association/American College of Cardiology/Heart Rhythm Society Guidelines. Circulation Arrhythmia And Electrophysiology 2017, 10: e005051. PMID: 29141842, DOI: 10.1161/circep.117.005051.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAmerican Heart AssociationAtrial FibrillationCardiologistsFemaleGuideline AdherenceHealthcare DisparitiesHumansMaleMiddle AgedPractice Guidelines as TopicPractice Patterns, Physicians'Process Assessment, Health CareQuality Indicators, Health CareRegistriesRetrospective StudiesTime FactorsTreatment OutcomeUnited StatesConceptsAmerican Heart Association/American CollegeAtrial fibrillationGuideline recommendationsAmerican CollegeCardiology/Heart Rhythm Society GuidelinesHeart Rhythm Society guidelinesAtrial fibrillation guidelinesGuideline-concordant careThird of patientsRisk-adjusted outcomesAntiarrhythmic medicationsGuideline concordanceMajor bleedingMedian CHAOutpatient registryVASc scoreAntithrombotic therapyCause hospitalizationMedian ageClinical outcomesSociety guidelinesORBIT-AFImproved outcomesPatient levelSimilar risk
2012
Procedural Complications, Rehospitalizations, and Repeat Procedures After Catheter Ablation for Atrial Fibrillation
Shah RU, Freeman JV, Shilane D, Wang PJ, Go AS, Hlatky MA. Procedural Complications, Rehospitalizations, and Repeat Procedures After Catheter Ablation for Atrial Fibrillation. Journal Of The American College Of Cardiology 2012, 59: 143-149. PMID: 22222078, PMCID: PMC5340189, DOI: 10.1016/j.jacc.2011.08.068.Peer-Reviewed Original ResearchConceptsAF ablationAF hospitalizationsPeriprocedural complicationsOlder ageCalifornia State Inpatient DatabaseFirst AF ablationInitial AF ablationPredictors of complicationsRate of readmissionAtrial fibrillation ablationKaplan-Meier analysisRisk of complicationsMultivariable logistic regressionNew treatment optionsPost-procedural outcomesState Inpatient DatabasesLarge general populationCryotherapy ablationArrhythmia recurrenceCause hospitalizationInpatient complicationsRecurrent AFAdult patientsProcedural complicationsCatheter ablation