Adaptation of the nematode Caenorhabditis elegans to extreme osmotic stress
Lamitina ST, Morrison R, Moeckel GW, Strange K. Adaptation of the nematode Caenorhabditis elegans to extreme osmotic stress. American Journal Of Physiology - Cell Physiology 2003, 286: c785-c791. PMID: 14644776, DOI: 10.1152/ajpcell.00381.2003.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PhysiologicalAnimalsCaenorhabditis elegansGene Expression Regulation, EnzymologicGlycerolGlycerol-3-Phosphate Dehydrogenase (NAD+)Glycerolphosphate DehydrogenaseOsmotic PressureSaline Solution, HypertonicWater-Electrolyte BalanceConceptsExtreme osmotic stressOsmotic stressCell osmoregulationHypertonic stressFunctional genomic analysisNematode Caenorhabditis elegansOrganic osmolyte glycerolPowerful model systemNumerous experimental advantagesCellular osmotic homeostasisCaenorhabditis elegansC. elegansCellular lifeNematode CaenorhabditisOsmolyte glycerolGenomic analysisOsmotic homeostasisGenetic basisOsmotic adaptationTranscriptional expressionOsmotic balanceMolecular understandingAccumulation of glycerolGlycerol accumulationNaCl agar