2014
Role of the Vector in Arbovirus Transmission
Conway MJ, Colpitts TM, Fikrig E. Role of the Vector in Arbovirus Transmission. Annual Review Of Virology 2014, 1: 71-88. PMID: 26958715, PMCID: PMC7809425, DOI: 10.1146/annurev-virology-031413-085513.Peer-Reviewed Original ResearchDisease vectorsDominant lethal geneArbovirus transmissionTransmission of arbovirusesLethal genesMolecular detailsTransgenic mosquitoesHost-seeking behaviorMosquito populationsArboviral diseasesGenomicsProteomicsPrevalence of diseaseNovel strategyGenesArbovirusesMicrobesImmunological controlGrowthVectorDiseaseSignificant diseasePathogensHostRole
2013
The lipoprotein La7 contributes to Borrelia burgdorferi persistence in ticks and their transmission to naïve hosts
Yang X, Hegde S, Shroder DY, Smith AA, Promnares K, Neelakanta G, Anderson JF, Fikrig E, Pal U. The lipoprotein La7 contributes to Borrelia burgdorferi persistence in ticks and their transmission to naïve hosts. Microbes And Infection 2013, 15: 729-737. PMID: 23774694, PMCID: PMC3769513, DOI: 10.1016/j.micinf.2013.06.001.Peer-Reviewed Original ResearchConceptsComplex enzootic cycleInner membrane proteinB. burgdorferi persistenceProtein-protein interactionsOuter membrane lipoproteinNaïve hostsSpirochete life cycleCo-immunoprecipitation studiesMammalian infectivityMembrane proteinsRedundant rolesMolecular detailsMammalian hostsMembrane lipoproteinGene expressionWild typeInfection cycleLiquid chromatography-mass spectrometry analysisPathogen survivalBiological significanceHost transmissionEnzootic cyclePathogen transmissionSpectrometry analysisLA7