2013
Mosquito Saliva Serine Protease Enhances Dissemination of Dengue Virus into the Mammalian Host
Conway MJ, Watson AM, Colpitts TM, Dragovic SM, Li Z, Wang P, Feitosa F, Shepherd DT, Ryman KD, Klimstra WB, Anderson JF, Fikrig E. Mosquito Saliva Serine Protease Enhances Dissemination of Dengue Virus into the Mammalian Host. Journal Of Virology 2013, 88: 164-175. PMID: 24131723, PMCID: PMC3911723, DOI: 10.1128/jvi.02235-13.Peer-Reviewed Original ResearchConceptsDengue virusDENV infectivityAedes aegypti salivaMurine lymph nodesSalivary gland extractsAegypti salivaPrevention of diseaseLymph nodesMosquito salivaDENV loadVivo modelSerine protease activityNovel targetViral attachmentViral infectivityVirus infectivitySerine protease inhibitorHeparan sulfate proteoglycanExtracellular matrix proteinsRNA knockdownProtease inhibitorsInfectivitySulfate proteoglycanCell migrationMammalian hosts
2001
Dissociation of Infectivity and Pathogenicity inBorrelia burgdorferi
Thomas V, Anguita J, Samanta S, Rosa P, Stewart P, Barthold S, Fikrig E. Dissociation of Infectivity and Pathogenicity inBorrelia burgdorferi. Infection And Immunity 2001, 69: 3507-3509. PMID: 11292785, PMCID: PMC98321, DOI: 10.1128/iai.69.5.3507-3509.2001.Peer-Reviewed Original Research