2008
A Differential Role for BB0365 in the Persistence of Borrelia burgdorferi in Mice and Ticks
Pal U, Dai J, Li X, Neelakanta G, Luo P, Kumar M, Wang P, Yang X, Anderson JF, Fikrig E. A Differential Role for BB0365 in the Persistence of Borrelia burgdorferi in Mice and Ticks. The Journal Of Infectious Diseases 2008, 197: 148-155. PMID: 18171298, DOI: 10.1086/523764.Peer-Reviewed Original ResearchConceptsVertebrate hostsWild-type B. burgdorferiArthropod vectorsB. burgdorferi persistenceB. burgdorferi transcriptomeDiverse murine tissuesSpirochete life cycleLife cycleB. burgdorferi B31Lyme disease agentGene productsMurine tissuesGenesWild rodentsDisease agentsDifferential rolesFeeding ticksB. burgdorferiInfectious isolatesHostBorrelia burgdorferiTicksTranscriptomePersistence of BorreliaMutants
2006
Borrelia burgdorferi Lacking BBK32, a Fibronectin-Binding Protein, Retains Full Pathogenicity
Li X, Liu X, Beck DS, Kantor FS, Fikrig E. Borrelia burgdorferi Lacking BBK32, a Fibronectin-Binding Protein, Retains Full Pathogenicity. Infection And Immunity 2006, 74: 3305-3313. PMID: 16714558, PMCID: PMC1479267, DOI: 10.1128/iai.02035-05.Peer-Reviewed Original ResearchConceptsB. burgdorferiFlat ticksB. burgdorferi proteinsTick biteSpirochete acquisitionLyme disease spirocheteAdverse effectsBorrelia burgdorferiFibronectin-binding proteinBurgdorferiFibronectin binding proteinMiceSpirochete life cycleLyme pathogenesisB. burgdorferi B31Mammalian hostsSyringe inoculationExpression profilesBBK32Surface lipoproteinsFibronectin bindingPathogenesisExpressionInfectionTemporal expression profiles