2015
Chemotherapy-related amenorrhea after adjuvant paclitaxel–trastuzumab (APT trial)
Ruddy KJ, Guo H, Barry W, Dang CT, Yardley DA, Moy B, Marcom PK, Albain KS, Rugo HS, Ellis MJ, Shapira I, Wolff AC, Carey LA, Overmoyer BA, Hudis C, Krop IE, Burstein HJ, Winer EP, Partridge AH, Tolaney SM. Chemotherapy-related amenorrhea after adjuvant paclitaxel–trastuzumab (APT trial). Breast Cancer Research And Treatment 2015, 151: 589-596. PMID: 25981899, PMCID: PMC5057177, DOI: 10.1007/s10549-015-3426-z.Peer-Reviewed Original ResearchConceptsChemotherapy-related amenorrheaChemotherapy initiationMenopausal symptomsBreast cancerAdjuvant breast cancer therapyEarly-stage breast cancerNode-negative HER2Weeks of paclitaxelStage breast cancerLast menstrual periodBreast cancer therapyAdjuvant paclitaxelAmenorrhea ratesAPT trialEligible patientsEvaluable populationPremenopausal womenAdjuvant studiesTrastuzumab monotherapyMedian timeMenstrual periodCancer regimensAmenorrheaTrastuzumabMonths
2012
Biomarkers of amenorrhea and ovarian function in breast cancer survivors.
Ruddy K, Gelber S, Tamimi R, Ginsburg E, Schapira L, Come S, Meyer M, Winer E, Partridge A. Biomarkers of amenorrhea and ovarian function in breast cancer survivors. Journal Of Clinical Oncology 2012, 30: 9071-9071. DOI: 10.1200/jco.2012.30.15_suppl.9071.Peer-Reviewed Original ResearchAnti-Mullerian hormoneBreast cancer survivorsOvarian functionBreast cancerCancer survivorsProspective multi-center cohort studyFollicle-stimulating hormone levelsMulti-center cohort studyYoung breast cancer survivorsResidual ovarian functionEarly breast cancerLast menstrual periodWilcoxon rank sum testRank sum testOvarian ablationEndocrine therapyOvarian suppressionCohort studyEligible womenFSH levelsOvarian reserveMedian ageOvarian dysfunctionSurvivorship periodMenopausal symptomsSexual functioning in young women with breast cancer.
Rosenberg S, Tamimi R, Gelber S, Ruddy K, Kereakoglow S, Borges V, Come S, Schapira L, Winer E, Partridge A. Sexual functioning in young women with breast cancer. Journal Of Clinical Oncology 2012, 30: 9100-9100. DOI: 10.1200/jco.2012.30.15_suppl.9100.Peer-Reviewed Original ResearchCancer Rehabilitation Evaluation SystemBreast cancerSexual functioningYoung womenMulti-center cohort studySexual interestRehabilitation Evaluation SystemBody imageAdjuvant therapyPain symptomsCohort studyDysfunction scorePoor body imageMusculoskeletal painSurvivorship periodMenopausal symptomsPoor functionCare scoresSexual dysfunctionActive womenStage 0Age 40Treatment groupsTreatment dataMultivariate analysis
2008
Applying a conceptual model for examining health‐related quality of life in long‐term breast cancer survivors: CALGB study 79804
Paskett ED, Herndon JE, Day JM, Stark NN, Winer EP, Grubbs SS, Pavy MD, Shapiro CL, List MA, Hensley ML, Naughton MA, Kornblith AB, Habin KR, Fleming GF, Bittoni MA. Applying a conceptual model for examining health‐related quality of life in long‐term breast cancer survivors: CALGB study 79804. Psycho-Oncology 2008, 17: 1108-1120. PMID: 18314912, PMCID: PMC3930158, DOI: 10.1002/pon.1329.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAntineoplastic Combined Chemotherapy ProtocolsBreast NeoplasmsChemotherapy, AdjuvantClimactericCombined Modality TherapyComorbidityDisease-Free SurvivalFemaleFollow-Up StudiesHealth BehaviorHumansLife StyleMiddle AgedNeoplasm StagingQuality of LifeRandomized Controlled Trials as TopicSick RoleSocial SupportSocioeconomic FactorsSpiritualitySurvivorsConceptsLong-term breast cancer survivorsHealth-related qualityBreast cancer survivorsHealth-oriented behaviorGlobal HRQLCancer survivorsGlobal health-related qualityBreast cancer patientsLow social supportCALGB 8541Vaginal drynessRegression modelsHot flashesMenopausal symptomsSurvivors' healthCancer patientsHeart diseaseHRQLLifestyle changesPsychosocial concernsPrevalence of problemsSurvivorsCancer diagnosisPrevalent problemSocial support
2006
Menopausal-type symptoms in young breast cancer survivors
Leining M, Gelber S, Rosenberg R, Przypyszny M, Winer E, Partridge A. Menopausal-type symptoms in young breast cancer survivors. Annals Of Oncology 2006, 17: 1777-1782. PMID: 16971671, DOI: 10.1093/annonc/mdl299.Peer-Reviewed Original ResearchConceptsYoung breast cancer survivorsBreast cancer survivorsOvarian suppressionCancer survivorsBreast cancerBreast Cancer Prevention Trial Symptom ChecklistBothersome menopausal symptomsAge 40 yearsTreatment decision makingLong-term qualityTime of surveyPrior chemotherapyPostmenopausal statusBothersome symptomsSymptom scoresHot flashesMenopausal symptomsAromatase inhibitorsInternet-based surveyBaseline anxietySymptom ChecklistSymptomsYoung womenSurvivorsWomen