1997
Regulation of CD34 expression in differentiating M1 cells.
Krause DS, Kapadia SU, Raj NB, May WS. Regulation of CD34 expression in differentiating M1 cells. Experimental Hematology 1997, 25: 1051-61. PMID: 9293902.Peer-Reviewed Original ResearchMeSH Keywords3T3 CellsAnimalsAntigens, CD34Base SequenceBinding SitesCell DifferentiationCells, CulturedDNA-Binding ProteinsDown-RegulationGene Expression RegulationGene Expression Regulation, DevelopmentalGene Expression Regulation, NeoplasticHematopoiesisLeukemia, MyeloidMiceMolecular Sequence DataNuclear ProteinsRNA, MessengerTranscription, GeneticConceptsTranscription initiation siteUntranslated regionPromoter activityHematopoietic stemCell type-specific expressionSecondary structureTATA-less promoterPromoter-luciferase reporter constructsFull promoter activityUpstream genomic DNAProgenitor cellsTranslation start siteMature blood cellsType-specific expressionOptimal promoter activityExtensive secondary structureP1 nuclease digestionCell-specific factorsTranscriptional initiationGene regulationTranscription factorsConsensus sitesStart siteRegulatory elementsTATA element
1994
Characterization of Murine CD34, a Marker for Hematopoietic Progenitor and Stem Cells
Krause D, Ito T, Fackler M, Smith O, Collector M, Sharkis S, May W. Characterization of Murine CD34, a Marker for Hematopoietic Progenitor and Stem Cells. Blood 1994, 84: 691-701. PMID: 7519070, DOI: 10.1182/blood.v84.3.691.691.Peer-Reviewed Original ResearchConceptsFull-length CD34Colony-forming unit-spleenM1 leukemia cellsMurine CD34Stem cellsHematopoietic progenitorsMurine hematopoietic stem cellsProgenitor cellsBone marrow cellsEmbryonic stem cellsHuman hematopoietic stemPotential functional differencesLong-term repopulating abilityCell linesFunctional hematopoietic progenitorsFull-length formCHO-K1 cell lineDifferent cell typesMurine cell linesPattern of expressionPA6 stromal cellsHematopoietic stem cellsLeukemia cellsHematopoietic progenitor cellsApparent molecular weight