About
Research
Publications
2019
Helminth‐derived molecules inhibit colitis‐associated colon cancer development through NF‐κB and STAT3 regulation
Callejas B, Mendoza‐Rodríguez M, Villamar‐Cruz O, Reyes‐Martínez S, Sánchez‐Barrera C, Rodríguez‐Sosa M, Delgado‐Buenrostro N, Martínez‐Saucedo D, Chirino Y, León‐Cabrera S, Pérez‐Plasencia C, Vaca‐Paniagua F, Arias‐Romero L, Terrazas L. Helminth‐derived molecules inhibit colitis‐associated colon cancer development through NF‐κB and STAT3 regulation. International Journal Of Cancer 2019, 145: 3126-3139. PMID: 31407335, DOI: 10.1002/ijc.32626.Peer-Reviewed Original ResearchConceptscolitis-associated colon cancernuclear factor kappa-light-chain-enhancermurine modelcolorectal cancercancer developmenthuman colonic epithelial cell linecolonic epithelial cell linenuclear factor kappa-light-chain-enhancer of activated B cellsfactor kappa-light-chain-enhancer of activated B cellsNF-kBcolon cancer developmentepithelial cell linestages of tumorigenesisIL-33IL-17B cellstumor progressionTaenia crassiceps‐Excreted/Secreted Products Induce a Defined MicroRNA Profile that Modulates Inflammatory Properties of Macrophages
Martínez-Saucedo D, de Dios Ruíz-Rosado J, Terrazas C, Callejas B, Satoskar A, Partida-Sánchez S, Terrazas L. Taenia crassiceps‐Excreted/Secreted Products Induce a Defined MicroRNA Profile that Modulates Inflammatory Properties of Macrophages. Journal Of Immunology Research 2019, 2019: 2946713. PMID: 31218234, PMCID: PMC6536978, DOI: 10.1155/2019/2946713.Peer-Reviewed Original Research
2018
Parasites as negative regulators of cancer
Callejas B, Martínez-Saucedo D, Terrazas L. Parasites as negative regulators of cancer. Bioscience Reports 2018, 38: bsr20180935. PMID: 30266743, PMCID: PMC6200699, DOI: 10.1042/bsr20180935.Peer-Reviewed Original ResearchConceptsregulation of inflammatory responsesinduction of apoptosisnegative regulatorhallmarks of canceradjuvant therapyprogression of cancermechanism of actionimmune responseantitumor actioninflammatory responsecancer progressioncancerproliferative signalsregulation of cancerbiological agentsparasitic diseasesinfectionbeneficial effectsantitumorparasitic infectionsdiseasehelminth parasitesAngiotensin II receptor I blockade prevents stenosis of tissue engineered vascular grafts
de Dios Ruiz‐Rosado J, Lee Y, Mahler N, Yi T, Robledo‐Avila F, Martinez‐Saucedo D, Lee AY, Shoji T, Heuer E, Yates AR, Pober JS, Shinoka T, Partida‐Sanchez S, Breuer CK. Angiotensin II receptor I blockade prevents stenosis of tissue engineered vascular grafts. The FASEB Journal 2018, 32: 6822-6832. PMID: 29906242, PMCID: PMC6219835, DOI: 10.1096/fj.201800458.Peer-Reviewed Original Researchangiotensin II receptor ITEVG stenosisprevents stenosismononuclear cellsangiotensin II type 1 receptor antagonistreceptor Ibone marrow-derived mononuclear cellsshort-term losartan treatmenttype 1 receptor antagonistmarrow-derived mononuclear cellsvascular graftsshort-term administrationcongenital heart surgerytissue-engineered vascular graftslong-term patencywidespread clinical uselosartan treatmentpharmacologic treatmentacute phasemonocyte infiltrationheart surgeryreceptor antagonistCCR2 knockoutrecipient miceclinical trials
2017
Helminth-induced Ly6Chi monocyte-derived alternatively activated macrophages suppress experimental autoimmune encephalomyelitis
. Helminth-induced Ly6Chi monocyte-derived alternatively activated macrophages suppress experimental autoimmune encephalomyelitis. Scientific Reports 2017, 7: 40814. PMID: 28094319, PMCID: PMC5240103, DOI: 10.1038/srep40814.Peer-Reviewed Original Research
2015
Uncovering Leishmania–macrophage interplay using imaging flow cytometry
. Uncovering Leishmania–macrophage interplay using imaging flow cytometry. Journal Of Immunological Methods 2015, 423: 93-98. PMID: 25967951, PMCID: PMC4620550, DOI: 10.1016/j.jim.2015.04.022.Peer-Reviewed Original ResearchThe Macrophage Galactose‐Type Lectin‐1 (MGL1) Recognizes Taenia crassiceps Antigens, Triggers Intracellular Signaling, and Is Critical for Resistance to This Infection
. The Macrophage Galactose‐Type Lectin‐1 (MGL1) Recognizes Taenia crassiceps Antigens, Triggers Intracellular Signaling, and Is Critical for Resistance to This Infection. BioMed Research International 2015, 2015: 615865. PMID: 25664320, PMCID: PMC4312580, DOI: 10.1155/2015/615865.Peer-Reviewed Original Research
Academic Achievements & Community Involvement
Teaching & Mentoring
Mentoring
Deanne Yugawa
Graduate student2022 - 2025
News
News
- July 16, 2025
Yale Researchers Develop Novel Antibody-RNA Therapy for Resistant Cancers
- May 28, 2025
Yale RNA Center Travel Grants Support Attendance at RNA 2025 in San Diego
- May 13, 2025
Yale representation at the Microsymposium on RNA Biology
- February 02, 2024
Innovative Researcher Dr. Giulia Biancon Honored with 2024 Eclipse Award