2023
Chemical interactions modulate λ6‐85 stability in cells
Knab E, Davis C. Chemical interactions modulate λ6‐85 stability in cells. Protein Science 2023, 32: e4698. PMID: 37313657, PMCID: PMC10288553, DOI: 10.1002/pro.4698.Peer-Reviewed Original Research
2019
Quantifying protein dynamics and stability in a living organism
Feng R, Gruebele M, Davis CM. Quantifying protein dynamics and stability in a living organism. Nature Communications 2019, 10: 1179. PMID: 30862837, PMCID: PMC6414637, DOI: 10.1038/s41467-019-09088-y.Peer-Reviewed Original Research
2018
Labeling for Quantitative Comparison of Imaging Measurements in Vitro and in Cells
Davis CM, Gruebele M. Labeling for Quantitative Comparison of Imaging Measurements in Vitro and in Cells. Biochemistry 2018, 57: 1929-1938. PMID: 29546761, DOI: 10.1021/acs.biochem.8b00141.Peer-Reviewed Original ResearchConceptsCell biologyComplex dissociation constantsProtein structureBiophysical experimentsModification sitesCell proteinsSuch measurementsQualitative imagingImaging measurementsBiologyCellsPowerful techniqueMeasurementsQuantitative measurementsTarget moleculesDissociation constantsRNAProteinQuantitative comparisonVitroLocalizationConstantsLabelingTarget
2017
How does solvation in the cell affect protein folding and binding?
Davis CM, Gruebele M, Sukenik S. How does solvation in the cell affect protein folding and binding? Current Opinion In Structural Biology 2017, 48: 23-29. PMID: 29035742, DOI: 10.1016/j.sbi.2017.09.003.Peer-Reviewed Original ResearchConceptsMild environmental changesProtein functionCellular processesProtein foldingCellular environmentProtein surface areaProtein studiesLive cellsEnvironmental changesNon-steric interactionsProtein processesNatural contextCellsInteraction typesSolute environmentFoldingProteinRecent examplesBindingRapid changesSolute composition