2014
Asthma medication use during pregnancy, wheeze and estimated exposure to ambient nitrogen dioxide
Gent JF, Kezik JM, Hill ME, McKay LA, Holford TR, Leaderer BP, Bracken MB. Asthma medication use during pregnancy, wheeze and estimated exposure to ambient nitrogen dioxide. European Respiratory Journal 2014, 45: 538-540. PMID: 25537555, PMCID: PMC4331059, DOI: 10.1183/09031936.00161514.Peer-Reviewed Original ResearchConceptsAsthma medication useMedication usePregnant womenRisk of wheezePoor pulmonary functionAdverse health outcomesPregnant asthmaticsAsthma exacerbationsAsthma medicationsPerinatal complicationsPulmonary functionFetal growthHealth outcomesPregnancyNO2 exposureWheezeAsthmaMedicationsWomenAmbient nitrogen dioxideMothersMinimal effectExposureAsthmaticsExacerbation
1995
Effect of nitrous acid on lung function in asthmatics: a chamber study.
Beckett W, Russi M, Haber A, Rivkin R, Sullivan J, Tameroglu Z, Mohsenin V, Leaderer B. Effect of nitrous acid on lung function in asthmatics: a chamber study. Environmental Health Perspectives 1995, 103: 372-375. PMID: 7607138, PMCID: PMC1519093, DOI: 10.1289/ehp.95103372.Peer-Reviewed Original ResearchConceptsSignificant airflow obstructionChamber exposure studiesFiltered room airModerate cycle exerciseNitrous acid exposureIndoor nitrogen dioxideMucous membrane symptomsDuration of exposureAirflow obstructionLung functionIrritant symptomsVital capacityCycle exerciseLung mechanicsRespiratory effectsAcid exposureRespiratory parametersAdult subjectsRoom airHealth effectsSymptomsSignificant decreaseAsthmaticsExposure studiesCommon indoor air pollutants
1987
An evaluation of respiratory effects following exposure to 2.0 ppm formaldehyde in asthmatics: lung function, symptoms, and airway reactivity.
Witek T, Schachter E, Tosun T, Beck G, Leaderer B. An evaluation of respiratory effects following exposure to 2.0 ppm formaldehyde in asthmatics: lung function, symptoms, and airway reactivity. Archives Of Environmental & Occupational Health 1987, 42: 230-7. PMID: 3310924.Peer-Reviewed Original ResearchConceptsMethacholine inhalation challenge testFlow-volume parametersInhalation challenge testSignificant airway obstructionAirway reactivityAirway obstructionAirway responsesAsthmatic volunteersLung functionSore throatAirway resistanceMethacholine concentrationModerate exerciseRespiratory effectsFormaldehyde exposurePpm exposureChallenge testSeparate daysEye irritationMedian decrementAsthmaticsSymptomsExposurePpm formaldehydeDegrees C
1986
Controlled human studies on the pulmonary effects of indoor air pollution: Experiences with sulful dioxide and formaldehyde
Witek T, Schachter E, Tosun T, Leaderer B, Beck G. Controlled human studies on the pulmonary effects of indoor air pollution: Experiences with sulful dioxide and formaldehyde. Environment International 1986, 12: 129-135. DOI: 10.1016/0160-4120(86)90023-1.Peer-Reviewed Original Research
1985
Respiratory symptoms associated with sulfur dioxide exposure
Witek T, Schachter E, Beck G, Cain W, Colice G, Leaderer B. Respiratory symptoms associated with sulfur dioxide exposure. International Archives Of Occupational And Environmental Health 1985, 55: 179-183. PMID: 3988360, DOI: 10.1007/bf00378381.Peer-Reviewed Original ResearchConceptsAsthmatic subjectsHealthy subjectsDose-dependent bronchoconstrictionLower airway symptomsUpper airway complaintsSeverity of complaintsLower respiratory complaintsSulfur dioxide exposureAirway complaintsAirway symptomsChest tightnessRespiratory symptomsRespiratory complaintsClinical significanceSymptomsComplaintsAsthmaticsSubjective responsesSensitive individualsSubjectsExposureLevels of SO2DyspneaBronchoconstrictionSeverity