2000
Metabolic Control From The Back Benches: Biochemistry Towards Biocomplexity
Westerhoff H, Teusink B, Mensonides F, Reijenga K, Esgalhado E, Kholodenko B, Somsen O, Van Heeswijk W, Boogerd F, Bruggeman F, Snoep J. Metabolic Control From The Back Benches: Biochemistry Towards Biocomplexity. NATO Science Partnership Subseries: 3 2000, 235-242. DOI: 10.1007/978-94-011-4072-0_26.Peer-Reviewed Original ResearchBacterial inner membraneElectron transfer chainImportant metabolic processesBiological free energy transductionFermentation of glucoseInner membraneATP hydrolysisPhysiological processesMetabolic processesMolecular biologyProton pumpLiving cellsStudy of metabolismProtein fractionsBiochemical reactionsIndependent chemical reactionsFree energy transductionBiochemistryChemical reactionsTransductionYeastBiocomplexityReactionBiologySubstantial progress
1993
The sum of the control coefficients of all enzymes on the flux through a group‐transfer pathway can be as high as two
van DAM K, van der VLAG J, KHOLODENKO B, WESTERHOFF H. The sum of the control coefficients of all enzymes on the flux through a group‐transfer pathway can be as high as two. The FEBS Journal 1993, 212: 791-799. PMID: 8462550, DOI: 10.1111/j.1432-1033.1993.tb17720.x.Peer-Reviewed Original ResearchConceptsGroup-transfer pathwaysReaction activityDissociation rate constantsElectron transfer chainAcceptor couplesEnzyme-enzyme interactionsEnzyme concentrationRate constantsEnzyme-enzyme complexEnzyme interactionsComplexesControl of enzymesEnzyme complexEnzymeConcentrationBacterial phosphoenolpyruvateMain pathwayInteractionConstantsChainControl analysisSimple metabolic pathwaysSugar phosphotransferase system