2013
Complexity of Receptor Tyrosine Kinase Signal Processing
Volinsky N, Kholodenko BN. Complexity of Receptor Tyrosine Kinase Signal Processing. Cold Spring Harbor Perspectives In Biology 2013, 5: a009043. PMID: 23906711, PMCID: PMC3721286, DOI: 10.1101/cshperspect.a009043.Peer-Reviewed Original ResearchConceptsCombinatorial varietySignal processingMathematical modelingSpecific system propertiesSpecific cell fate decisionsSystem propertiesNetwork behaviorReceptor tyrosine kinasesMultiple feedsSpatiotemporal dynamicsComputational approachExcitable responseIntricate landscapeCell fate decisionsSpecific cellular outcomesPathway cross talkOscillationsBistabilityNetwork circuitryDynamicsModelingTranscriptional controlAdapts cellsCellular outcomes
2012
Understanding Cell Fate Decisions by Identifying Crucial System Dynamics
Fey D, Croucher D, Kolch W, Kholodenko B. Understanding Cell Fate Decisions by Identifying Crucial System Dynamics. SEMA SIMAI Springer Series 2012, 83-104. DOI: 10.1007/978-88-470-2571-4_5.Peer-Reviewed Original Research