Boby Mathew
Associate Research ScientistCards
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Research
Publications
2026
Cell-type-specific proximity labeling of organ secretomes reveals energy balance-dependent proteomic remodeling
Plucińska K, Wayne C, Sanford H, Mathew B, Ropek N, Adaniya S, Model C, Gómez-Banoy N, Morozova K, Cao X, Friedman J, Loh K, Cohen P, Vinogradova E. Cell-type-specific proximity labeling of organ secretomes reveals energy balance-dependent proteomic remodeling. Cell Reports 2026, 45: 117507. PMID: 42284144, PMCID: PMC13465167, DOI: 10.1016/j.celrep.2026.117507.Peer-Reviewed Original ResearchBeta cell-derived cholecystokinin drives obesity-associated pancreatic adenocarcinoma development
Garcia C, Venkat A, McQuaid D, Agabiti S, Tong A, Mathew B, Cardone R, Starble R, Ruiz C, Zheng C, Sogunro A, Jacox J, Loh K, Kibbey R, Krishnaswamy S, Muzumdar M. Beta cell-derived cholecystokinin drives obesity-associated pancreatic adenocarcinoma development. Nature Communications 2026, 17: 3292. PMID: 41760660, PMCID: PMC13066563, DOI: 10.1038/s41467-026-69821-2.Peer-Reviewed Original ResearchThis study investigates how obesity-induced cholecystokinin (CCK) expression in pancreatic beta cells drives pancreatic cancer development by altering cellular signaling within the environment of arising tumors, suggesting potential therapeutic targets.Global field trials show the advantages of beta regression compared with logit transformation and quasi‐likelihood for the analysis of percentage plant disease severity
Mathew B, Lancashire P, Rutten M. Global field trials show the advantages of beta regression compared with logit transformation and quasi‐likelihood for the analysis of percentage plant disease severity. Annals Of Applied Biology 2026, 188: 904-916. DOI: 10.1111/aab.70094.Peer-Reviewed Original Research
2025
Unraveling breast cancer risk with a focus on menopausal status: a large case–control study
Jacob J, George P, Mathew B, Nair R, Mathew A. Unraveling breast cancer risk with a focus on menopausal status: a large case–control study. Cancer Causes & Control 2025, 37: 15. PMID: 41455010, DOI: 10.1007/s10552-025-02090-4.Peer-Reviewed Original ResearchNAMS task force report on breast cancer in India
Gupta S, Batra A, Prinja S, Malhotra H, Mohanapriya T, Thomas S, Chatterjee S, Shet T, Thulkar S, Mathew B. NAMS task force report on breast cancer in India. Annals Of The National Academy Of Medical Sciences (India) 2025, 61: 132-170. DOI: 10.25259/anams_tfr_14_2024.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2024
Comparison of prone versus supine position for whole breast radiotherapy following breast conservation: A dosimetric study
Gopikrishna M, Babu G, Raghavan R, Gopalakrishnan Z, Menon S, George P, Mathew B. Comparison of prone versus supine position for whole breast radiotherapy following breast conservation: A dosimetric study. Journal Of Cancer Research And Therapeutics 2024, 20: 1866-1871. DOI: 10.4103/jcrt.jcrt_1312_23.Peer-Reviewed Original ResearchTrastuzumab emtansine induced hyponatremia in breast cancer - A case report.
Pareeth F, Babu G, Mathew B. Trastuzumab emtansine induced hyponatremia in breast cancer - A case report. Journal Of Cancer Research And Therapeutics 2024, 21: 240-242. PMID: 39207114, DOI: 10.4103/jcrt.jcrt_1602_23.Peer-Reviewed Original ResearchComparison of imaging modalities for the accurate delineation of arteriovenous malformations (AVM) and evaluation of setup accuracy with reference to non-invasive LINAC-based stereotactic radiosurgery (SRS).
Sukumaran A, Raghavan R, Mathew B, Bhasi S, Koshi S, Krishna K. Comparison of imaging modalities for the accurate delineation of arteriovenous malformations (AVM) and evaluation of setup accuracy with reference to non-invasive LINAC-based stereotactic radiosurgery (SRS). Journal Of Cancer Research And Therapeutics 2024, 20: 874-880. PMID: 39023594, DOI: 10.4103/jcrt.jcrt_938_21.Peer-Reviewed Original ResearchCOVID-19 Impact on Newly Diagnosed Breast Cancers at Regional Cancer Centre, Thiruvananthapuram—An Audit
Babu G, Rajeev K, Mathew A, Arjunan A, Priya B, Bhargavan R, Augustine P, Cherian K, Joseph R, Radhakrishnan N, Mathew B. COVID-19 Impact on Newly Diagnosed Breast Cancers at Regional Cancer Centre, Thiruvananthapuram—An Audit. South Asian Journal Of Cancer 2024, 13: 045-050. PMID: 38721099, PMCID: PMC11076073, DOI: 10.1055/s-0044-1779251.Peer-Reviewed Original Research
2022
RhoC in association with TET2/WDR5 regulates cancer stem cells by epigenetically modifying the expression of pluripotency genes
Thomas P, Srivastava S, Udayashankara A, Damodaran S, Yadav L, Mathew B, Suresh S, Mandal A, Srikantia N. RhoC in association with TET2/WDR5 regulates cancer stem cells by epigenetically modifying the expression of pluripotency genes. Cellular And Molecular Life Sciences 2022, 80: 1. PMID: 36469134, PMCID: PMC11073244, DOI: 10.1007/s00018-022-04645-z.Peer-Reviewed Original Research
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