Both proliferation and lipogenesis of brown adipocytes contribute to postnatal brown adipose tissue growth in mice
Negron SG, Ercan-Sencicek AG, Freed J, Walters M, Lin Z. Both proliferation and lipogenesis of brown adipocytes contribute to postnatal brown adipose tissue growth in mice. Scientific Reports 2020, 10: 20335. PMID: 33230135, PMCID: PMC7683731, DOI: 10.1038/s41598-020-77362-x.Peer-Reviewed Original ResearchConceptsBrown adipocytesExit cell cycleDevelopmental dynamicsCell cycle activityBrown adipose tissueDifferent growth phasesMolecular mechanismsCell cycleFluorescence-activated cell sorting (FACS) analysisCell sorting (FACS) analysisBAT growthGrowth phaseEssential roleInterscapular BATCycle activityTissue growthDevelopment of BATBrown adipose tissue growthAdipocytesAdipose tissue growthInterscapular brown adipose tissueProliferationGrowthEmbryogenesisLipogenesis