2024
Trends in American Indian/Alaskan native self-reported stroke prevalence and associated modifiable risk factors in the United States from 2011-2021
Heath T, Shrishail N, Wong K, Johnston K, Sharma R, Ney J, Sheth K, de Havenon A. Trends in American Indian/Alaskan native self-reported stroke prevalence and associated modifiable risk factors in the United States from 2011-2021. Journal Of Stroke And Cerebrovascular Diseases 2024, 33: 107650. PMID: 38460776, PMCID: PMC11253029, DOI: 10.1016/j.jstrokecerebrovasdis.2024.107650.Peer-Reviewed Original ResearchBehavioral Risk Factor Surveillance SystemSelf-reported strokeModifiable vascular risk factorsVascular risk factorsPrevalence of strokeStroke prevalenceRisk factorsPrevalence of self-reported strokeWhite adultsBehavioral Risk Factor Surveillance System surveyRisk Factor Surveillance SystemPersistent health disparitiesAmerican Indian/Alaskan NativesSurvey of adultsModifiable risk factorsHigher overall burdenSurvey-weighted prevalenceUnited StatesHealth disparitiesRace/ethnic groupsRisk of strokeAI/ANOverall burdenRate of strokeSelf-report
2023
Higher Hospital Frailty Risk Score Is Associated With Increased Risk of Stroke: Observational and Genetic Analyses
Renedo D, Acosta J, Koo A, Rivier C, Sujijantarat N, de Havenon A, Sharma R, Gill T, Sheth K, Falcone G, Matouk C. Higher Hospital Frailty Risk Score Is Associated With Increased Risk of Stroke: Observational and Genetic Analyses. Stroke 2023, 54: 1538-1547. PMID: 37216451, PMCID: PMC10212531, DOI: 10.1161/strokeaha.122.041891.Peer-Reviewed Original ResearchConceptsHospital Frailty Risk ScoreRisk of strokeHighest Hospital Frailty Risk ScoresDate of consentFrailty Risk ScoreMendelian randomization analysisStroke riskRisk scoreRandomization analysisTime of enrollmentAvailable electronic health recordsMendelian randomizationElectronic health recordsLook-back periodIncident strokeDose-response wayFrailty statusHemorrhagic strokeMultivariable analysisStroke eventsObservational studyHigh riskFrailtySignificant associationSimilar associationChange in Smoking Behavior and Outcome After Ischemic Stroke: Post-Hoc Analysis of the SPS3 Trial
Anadani M, Turan T, Yaghi S, Spiotta A, Gory B, Sharma R, Sheth K, de Havenon A. Change in Smoking Behavior and Outcome After Ischemic Stroke: Post-Hoc Analysis of the SPS3 Trial. Stroke 2023, 54: 921-927. PMID: 36876480, PMCID: PMC10050138, DOI: 10.1161/strokeaha.121.038202.Peer-Reviewed Original ResearchConceptsMajor adverse cardiovascular eventsAdverse cardiovascular eventsAcute ischemic strokeIschemic strokeCardiovascular eventsPersistent smokersPersistent smokingSPS3 trialSmoking statusMyocardial infarctionMajor adverse cardiovascular events outcomesCardiovascular event outcomesMajor cardiovascular outcomesSubsequent cardiovascular eventsHistory of hypertensionRisk of strokeEnd of studyPost Hoc AnalysisPrior smokersRandomization armCardiovascular outcomesFormer smokersMonth 3Primary outcomeTotal cohortAssociation Between Hospital-Documented Atrial Fibrillation and Central Retinal Artery Occlusion
Lusk J, Song A, Unnithan S, Al-Khalidi H, Delic A, de Havenon A, Biousse V, Schrag M, Poli S, Piccini J, Xian Y, O’Brien E, Mac Grory B. Association Between Hospital-Documented Atrial Fibrillation and Central Retinal Artery Occlusion. Stroke 2023, 54: 983-991. PMID: 36729390, PMCID: PMC11173326, DOI: 10.1161/strokeaha.122.042292.Peer-Reviewed Original ResearchConceptsCentral retinal artery occlusionRetinal artery occlusionCardiovascular comorbiditiesArtery occlusionAtrial fibrillationInverse associationNon-Hispanic white race/ethnicityState Emergency Department DatabasesWhite race/ethnicityPrespecified sensitivity analysisPrimary end pointRisk of strokeCause-specific hazards modelEmergency Department DatabasesEmergency department settingPrimary risk factorState Inpatient DatabasesPositive control outcomesRace/ethnicityMedian followCohort studyCumulative incidenceIschemic strokeAF statusInpatient Database
2020
Diabetic Retinopathy and Risk of Stroke
Wong KH, Hu K, Peterson C, Sheibani N, Tsivgoulis G, Majersik JJ, de Havenon AH. Diabetic Retinopathy and Risk of Stroke. Stroke 2020, 51: 3733-3736. PMID: 33019896, PMCID: PMC7686117, DOI: 10.1161/strokeaha.120.030350.Peer-Reviewed Original ResearchConceptsBlood pressure interventionsRisk of strokeDiabetic retinopathyRandomization armIncident strokePrimary outcomePressure interventionPresence of DRCox proportional hazards modelACCORD Eye StudyRapid vision lossSubsequent stroke eventsCommon microvascular complicationCox regression modelProportional hazards modelMacrovascular complicationsMicrovascular complicationsHazard ratioEye StudyMicrovascular pathologyStroke eventsStudy baselineSerum glucoseVision lossHazards model
2017
Carotid intraplaque hemorrhage on vessel wall MRI does not correlate with TCD emboli monitoring in patients with recently symptomatic carotid atherosclerosis
de Havenon A, Tirschwell D, Majersik JJ, McNally S, Stoddard G, Moore A, Mossa-Basha M. Carotid intraplaque hemorrhage on vessel wall MRI does not correlate with TCD emboli monitoring in patients with recently symptomatic carotid atherosclerosis. The Neuroradiology Journal 2017, 30: 486-489. PMID: 28631982, PMCID: PMC5602332, DOI: 10.1177/1971400917707351.Peer-Reviewed Original ResearchConceptsAcute ischemic strokeSymptomatic carotid atherosclerosisCarotid atherosclerosisMicroembolic signalsIntraplaque hemorrhageCarotid intraplaque hemorrhageTranscranial DopplerVessel wall MRIIschemic strokeEmboli monitoringPresence of IPHRecent acute ischemic strokeTransient ischemic attackWarrants prospective studiesAcute stroke patientsRetrospective chart reviewRisk of strokeIschemic attackChart reviewProspective studyStroke patientsResults TwentyInclusion criteriaLarge cohortVolumetric MRI